Ahmed Mohamed Omar, Abouzeed Yousef M, Daw Mohamed Ali
Department of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya.
Open Vet J. 2025 Feb;15(2):533-540. doi: 10.5455/OVJ.2025.v15.i2.4. Epub 2025 Feb 28.
Colistin (polymyxin E) is a former exclusive veterinary antimicrobial and one of the oldest antibiotics that is currently recognized as one of the highest priority and critically important antimicrobials for human medicine. For food animals, colistin is extensively used for multiple medical and nonmedical purposes, particularly for growth promotion, prophylaxis/metaphylaxis, and therapeutic purposes. As a result, colistin resistance is widespread along the food chain and is linked to multidrug-resistant bacterial infections in humans. Furthermore, human medicine is more reliant on colistin for serious infections in healthcare settings. As a result, different types of national bans/restrictions in food- producing animals have been implemented around the world.
The testimonies of 29 countries representing global initiatives to phase-out colistin use in animal production.
黏菌素（多黏菌素E）曾是一种仅用于兽医的抗菌药物，也是最古老的抗生素之一，目前被认为是人类医学中最优先且至关重要的抗菌药物之一。对于食用动物，黏菌素被广泛用于多种医疗和非医疗目的，特别是用于生长促进、预防/群体预防以及治疗目的。因此，黏菌素耐药性在食物链中广泛存在，并与人类的多重耐药细菌感染有关。此外，人类医学在医疗环境中治疗严重感染时对黏菌素的依赖程度更高。因此，世界各地已对食用动物实施了不同类型的国家禁令/限制措施。
来自29个国家的证词代表了全球逐步淘汰动物生产中黏菌素使用的倡议。
