Tang Fengqin, Qi Shengcai, Tang Xiaoshan, Wen Xueyun, Zhang Yiming, Peng Guotao, Huang Jieying, Shang Guangwei, Zhang Xu, Chen Fubo, Xu Yuanzhi, Cai Jing
Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Department of Prosthodontics, Shanghai Stomatology Hospital, Fudan University, Shanghai, China.
Environ Toxicol. 2025 Oct;40(10):1207-1219. doi: 10.1002/tox.24519. Epub 2025 Apr 9.
Particulate matter with aerodynamic diameter ≤ 2.5 μm (PM) at high concentrations in dental clinics poses significant health risks to healthcare professionals. However, the morphology and chemical composition of PM in specific environments are not yet fully elucidated. In this study, we investigated the concentration, morphology, chemical composition, and health assessment of PM collected in a multi-chair dental clinic in Shanghai, China. Scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) were performed to observe the morphology and elemental composition of indoor and outdoor PM. Chemicals were measured for their concentrations using X-ray fluorescence spectrometry (XRF). In the dental clinic, the indoor PM concentration ranged from 2.01 to 114.59 μg/m, with a mean of 23.31 μg/m, while the outdoor PM concentration ranged from 2.88 to 157.4 μg/m, with a mean of 30.98 μg/m. Indoor particles showed more rough, irregular mineralization, which was confirmed as the dominant elements of Ca, P, Si, and zirconia (Zr) by EDS. The average concentrations of Ca, P, Cu, Sr, and Sb indoors were lower than those outdoors (p < 0.05). We also found that Cd, As, and Ni exceeded the annual limits of the Ambient Air Quality Standards of WHO. For the health assessment, the carcinogenic risks of Cd, As, and Cr were higher than the minimum acceptable level (1 × 10), with values of 3.68 × 10, 1.10 × 10, and 5.52 × 10, respectively, and the non-carcinogenic risk of Cd was the highest, as illustrated by the Hazard Quotient of 2.04. These findings indicate that dental healthcare professionals may be exposed to PM containing high concentrations of toxic metals and carcinogenic elements over the long term. This study highlights the importance of protective measures (e.g., the adoption of efficient air purification systems) to minimize the risk of particle inhalation for both patients and professionals.
牙科诊所中高浓度的空气动力学直径≤2.5μm的颗粒物(PM)对医护人员构成了重大健康风险。然而,特定环境中PM的形态和化学成分尚未完全阐明。在本研究中,我们调查了在中国上海一家多椅位牙科诊所收集的PM的浓度、形态、化学成分及健康评估。采用扫描电子显微镜(SEM)和能量色散X射线光谱仪(EDS)观察室内和室外PM的形态和元素组成。使用X射线荧光光谱法(XRF)测量化学物质的浓度。在牙科诊所中,室内PM浓度范围为2.01至114.59μg/m,平均为23.31μg/m,而室外PM浓度范围为2.88至157.4μg/m,平均为30.98μg/m。室内颗粒显示出更粗糙、不规则的矿化,通过EDS确认其主要元素为钙(Ca)、磷(P)、硅(Si)和氧化锆(Zr)。室内钙、磷、铜、锶和锑的平均浓度低于室外(p<0.05)。我们还发现,镉(Cd)、砷(As)和镍(Ni)超过了世界卫生组织《环境空气质量标准》的年度限值。对于健康评估,镉、砷和铬的致癌风险高于最低可接受水平(1×10),分别为3.68×10、1.10×10和5.52×10,镉的非致癌风险最高,危险商数为2.04。这些发现表明,牙科医护人员可能长期暴露于含有高浓度有毒金属和致癌元素的PM中。本研究强调了采取保护措施(如采用高效空气净化系统)以尽量减少患者和医护人员吸入颗粒物风险的重要性。