文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期,新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

电刺激对类风湿关节炎患者功能障碍和疼痛的疗效及安全性:一项随机对照试验的系统评价和网络荟萃分析方案

Efficacy and safety of electrical stimulation for functional impairment and pain in patients with rheumatoid arthritis: a protocol for systematic review and network meta-analysis of RCTs.

作者信息

Liao Zhichao, Tan Xinzhe, Liu Yichang, Li Wenqiang, Wang Gengjian, Wang Dongyan

机构信息

Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang, China.

Heilongjiang University of Chinese Medicine Affiliated Second Hospital, Harbin, Heilongjiang, China

出版信息

BMJ Open. 2025 Apr 9;15(4):e095309. doi: 10.1136/bmjopen-2024-095309.


DOI:10.1136/bmjopen-2024-095309
PMID:40204328
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11987110/
Abstract

OBJECTIVE: Several studies have indicated that transcutaneous electrical nerve stimulation, functional electrical stimulation, neuromuscular electrical stimulation and electroacupuncture exhibit certain therapeutic effects in the treatment of rheumatoid arthritis (RA). However, definitive proof of the effectiveness of different types of electrical stimulation in relieving the different symptomatic manifestations of RA is required. This study aims to analyse the efficacy (health assessment questionnaire, visual analogue scale, etc), safety (adverse reactions) of electrical stimulation for functional impairment (morning stiffness and decreased muscle strength) and pain (joint tenderness and swelling) of RA, and to explore their comparative advantages and potential benefits for patients. METHODS: We will conduct a systematic and comprehensive search of eight databases, and the search will proceed from the beginning to 5 September 2024. Two reviewers will independently screen the retrieved literature to determine the final included studies. Two reviewers will independently assess the risk of bias for all included eligible studies using the Cochrane Risk of Bias tool (V.2.0). Data synthesis will be performed using a random-effects model for network meta-analysis to compare the efficacy and safety of different electrical stimulations. The surface under the cumulative ranking curve will be used to demonstrate the probability of the benefits and harms of interventions. Funnel plots will be used to detect potential publication bias and small sample study effects. The strength of the evidence will be assessed through the Grading of Recommendations, Assessment, Development and Evaluation framework. ETHICS AND DISSEMINATION: Our study data comes from public databases, and the entire study does not directly involve patients and the public, so ethical approval is not required. The final study results will be peer-reviewed and published in a journal. PROSPERO REGISTRATION NUMBER: CRD42024586835.

摘要

目的:多项研究表明,经皮电神经刺激、功能性电刺激、神经肌肉电刺激和电针在类风湿关节炎(RA)治疗中显示出一定疗效。然而,需要确凿证据证明不同类型的电刺激在缓解RA不同症状表现方面的有效性。本研究旨在分析电刺激对RA功能障碍(晨僵和肌肉力量下降)和疼痛(关节压痛和肿胀)的疗效(健康评估问卷、视觉模拟量表等)、安全性(不良反应),并探讨其对患者的比较优势和潜在益处。 方法:我们将对八个数据库进行系统全面的检索,检索时间从开始至2024年9月5日。两名评审员将独立筛选检索到的文献以确定最终纳入的研究。两名评审员将使用Cochrane偏倚风险工具(V.2.0)独立评估所有纳入的合格研究的偏倚风险。将使用随机效应模型进行网络荟萃分析来比较不同电刺激的疗效和安全性。累积排序曲线下面积将用于展示干预措施利弊的概率。漏斗图将用于检测潜在的发表偏倚和小样本研究效应。将通过推荐分级、评估、制定和评价框架评估证据的强度。 伦理与传播:我们的研究数据来自公共数据库,整个研究不直接涉及患者和公众,因此无需伦理批准。最终研究结果将经过同行评审并发表在期刊上。 PROSPERO注册号:CRD42024586835。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17ec/11987110/22634f18a597/bmjopen-15-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17ec/11987110/22634f18a597/bmjopen-15-4-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17ec/11987110/22634f18a597/bmjopen-15-4-g001.jpg

相似文献

[1]
Efficacy and safety of electrical stimulation for functional impairment and pain in patients with rheumatoid arthritis: a protocol for systematic review and network meta-analysis of RCTs.

BMJ Open. 2025-4-9

[2]
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.

Cochrane Database Syst Rev. 2021-4-19

[3]
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.

Cochrane Database Syst Rev. 2020-1-9

[4]
Somatosensory stimulation treatments for postoperative analgesia of mixed hemorrhoids: Protocol for a systematic review and network meta-analysis.

Medicine (Baltimore). 2019-2

[5]
Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis.

Cochrane Database Syst Rev. 2017-12-22

[6]
Balneotherapy (or spa therapy) for rheumatoid arthritis.

Cochrane Database Syst Rev. 2015-4-11

[7]
Immunomodulatory therapies in community-acquired pneumonia: a protocol for a systematic review and network meta-analysis.

BMJ Open. 2025-7-10

[8]
Efficacy of non-pharmacological interventions on depressive symptoms in patients with Parkinson's disease: a study protocol for a systematic review and network meta-analysis.

BMJ Open. 2023-5-2

[9]
Transcutaneous electrical nerve stimulation (TENS) for fibromyalgia in adults.

Cochrane Database Syst Rev. 2017-10-9

[10]
Transcutaneous electrical nerve stimulation (TENS) for dementia.

Cochrane Database Syst Rev. 2003

本文引用的文献

[1]
Rheumatoid arthritis.

Lancet. 2023-11-25

[2]
Therapeutic advances in rheumatoid arthritis.

BMJ. 2024-1-17

[3]
2022 American College of Rheumatology Guideline for Exercise, Rehabilitation, Diet, and Additional Integrative Interventions for Rheumatoid Arthritis.

Arthritis Care Res (Hoboken). 2023-8

[4]
Interpreting and assessing confidence in network meta-analysis results: an introduction for clinicians.

J Anesth. 2022-8

[5]
Comparison of Efficacy of Acupuncture-Related Therapy in the Treatment of Rheumatoid Arthritis: A Network Meta-Analysis of Randomized Controlled Trials.

Front Immunol. 2022

[6]
Meta-analysis of prevalence: I statistic and how to deal with heterogeneity.

Res Synth Methods. 2022-5

[7]
2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.

Arthritis Care Res (Hoboken). 2021-7

[8]
Short-term transcutaneous non-invasive vagus nerve stimulation may reduce disease activity and pro-inflammatory cytokines in rheumatoid arthritis: results of a pilot study.

Scand J Rheumatol. 2021-1

[9]
Nonpharmacological treatment in established rheumatoid arthritis.

Best Pract Res Clin Rheumatol. 2020-1-25

[10]
Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis.

Br J Sports Med. 2019-10-30

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索