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同期腹腔镜袖状胃切除术与食管裂孔疝修补术治疗重度肥胖患者胃食管反流病的疗效:一项倾向评分匹配分析

Outcomes of Concomitant Laparoscopic Sleeve Gastrectomy and Hiatal Hernia Repair on Gastroesophageal Reflux Disease in Patients with Severe Obesity: A Propensity Score-Matched Analysis.

作者信息

El Nakeeb Ayman, Aldossary Hassan, Zaid Ahmed, Rashad Aly E, Balata Mohamed, Abdulrazek Mohamed, Alshehri Dafer, Hamza Hosam Mohamad, Elsheemy Reem, Mohammed Mohammed M, Alnakeeb Kareem, Attia Mohamed

机构信息

Mansoura University, Al Mansurah, Egypt.

Kingdom of Saudi Arabia, Wadi Al Dawasir Armed Forces Hospital, Wadi Al Dawaser, Saudi Arabia.

出版信息

Obes Surg. 2025 May;35(5):1685-1692. doi: 10.1007/s11695-025-07815-7. Epub 2025 Apr 9.

Abstract

BACKGROUND

Hiatal hernia (HH) is frequent in patients with obesity who have undergone bariatric surgery, but there is controversy about HH repair (HHR) during bariatric surgery. This study aimed to analyze the safety and efficacy of concomitant laparoscopic sleeve gastrectomy (LSG) and HHR in patients with severe obesity.

METHODS

A propensity score-matched analysis was conducted for patients who underwent LSG. Preoperative barium meal, upper endoscopy, and intraoperative findings were used to diagnose HH. The GERD health-related quality of life (GERD-HRQL) questionnaire was used to diagnose gastroesophageal reflux disease (GERD). Patients were divided into two groups: one underwent concomitant LSG with HHR and the other underwent LSG only. HHR was performed by cruroplasty and reconstruction of the phrenoesophageal ligament (PEL). Gastropexy was performed by fixing the gastric tube to the omentum and peripancreatic fascia. Outcomes included blood loss, operative time, postoperative complications, GERD, and percent excess weight loss.

RESULTS

Of the 406 patients included in the study, 203 patients with HH underwent LSG with HHR, while 203 underwent LSG alone. There was significantly longer operative time in the LSG with HHR group, but no statistical difference between the groups regarding postoperative complications, except postoperative GERD. De novo GERD symptoms developed significantly in the LSG only group. These results indicate that concomitant LSG with HHR leads to improvement of GERD and decreases the rate of de novo GERD symptoms.

CONCLUSIONS

HH should be repaired by cruroplasty and reconstruction of the PEM during LSG. HHR helps to improve postoperative GERD symptoms.

摘要

背景

食管裂孔疝(HH)在接受减重手术的肥胖患者中很常见,但关于减重手术期间HH修复(HHR)存在争议。本研究旨在分析同期腹腔镜袖状胃切除术(LSG)与HHR治疗重度肥胖患者的安全性和有效性。

方法

对接受LSG的患者进行倾向评分匹配分析。术前钡餐、上消化道内镜检查及术中发现用于诊断HH。采用胃食管反流病健康相关生活质量(GERD-HRQL)问卷诊断胃食管反流病(GERD)。患者分为两组:一组接受LSG同期HHR,另一组仅接受LSG。HHR通过膈肌成形术和食管膈韧带(PEL)重建进行。胃固定术通过将胃管固定于大网膜和胰腺周围筋膜来完成。观察指标包括失血量、手术时间、术后并发症、GERD及超重减轻百分比。

结果

本研究纳入的406例患者中,203例HH患者接受了LSG同期HHR,203例仅接受LSG。LSG同期HHR组手术时间明显更长,但除术后GERD外,两组术后并发症无统计学差异。仅接受LSG组新发GERD症状明显增多。这些结果表明,LSG同期HHR可改善GERD并降低新发GERD症状的发生率。

结论

在LSG期间应通过膈肌成形术和PEM重建修复HH。HHR有助于改善术后GERD症状。

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