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AUSS/UNSES-TLIF治疗单节段退变性腰椎管狭窄症的临床疗效:一项回顾性研究。

Clinical efficacy of AUSS/UNSES-TLIF in the treatment of single-segment degenerative lumbar spinal stenosis: a retrospective study.

作者信息

Liu Zhide, Hao Shiyuan, Li XiangLong, Song En, Yao Yabo

机构信息

Department of Spine Surgery, Second Affiliated Hospital of Xi'an Medical University, Xi'an, China.

Department of Sports Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China.

出版信息

J Orthop Surg Res. 2025 Apr 9;20(1):352. doi: 10.1186/s13018-025-05779-z.

DOI:10.1186/s13018-025-05779-z
PMID:40205552
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11980218/
Abstract

OBJECTIVE

To explore the clinical efficacy and advantages of Arthroscopic-assisted Uni-portal Spinal Surgery (AUSS)-Transforaminal Lumbar Interbody Fusion (TLIF) in the treatment of degenerative lumbar spinal stenosis (LSS).

METHODS

This study included 71 patients with lumbar spinal stenosis who underwent surgical treatment at the Department of Spine Surgery, Second Affiliated Hospital of Xi'an Medical University, between January 2022 and December 2023. Among these, 34 patients underwent AUSS-TLIF surgery, and 37 patients underwent minimally invasive TLIF (MIS-TLIF) surgery. Preoperative and postoperative Visual Analog Scale (VAS) scores for low back and leg pain, Oswestry Disability Index (ODI) scores, intervertebral disc height, anterior-posterior diameter of the canal (APDC), surgical-related parameters (such as operative time, intraoperative blood loss, postoperative drainage, postoperative C-reactive protein levels, and length of hospital stay), and surgical outcomes were compared and analyzed between the AUSS-TLIF and MIS-TLIF groups.

RESULTS

All 71 patients were followed up. There were no significant differences in preoperative VAS scores or ODI index between the AUSS-TLIF and MIS-TLIF groups (P > 0.05). Three days postoperatively, both groups showed significant reductions in back and leg symptoms, with VAS scores significantly lower than preoperatively (P < 0.05). However, the AUSS-TLIF group had lower VAS scores at 3 days and 3 months postoperatively compared to the MIS-TLIF group, with a statistically significant difference (P < 0.05). At 12 months postoperatively, there was no significant difference in VAS scores between the two groups (P > 0.05). Both groups showed significant improvement in lumbar function at 3 and 12 months postoperatively, with ODI scores significantly lower than preoperatively (P < 0.05). However, the AUSS-TLIF group had a significantly lower ODI score at 3 months postoperatively compared to the MIS-TLIF group (P < 0.05), with no significant difference at 12 months (P > 0.05). There were no significant differences in preoperative intervertebral disc height or APDC between the two groups (P > 0.05). CT scans at 12 months postoperatively showed a significant increase in intervertebral disc height and APDC in both groups compared to preoperative values (P < 0.05), with no significant difference between the groups (P > 0.05). The AUSS-TLIF group had lower surgical blood loss, postoperative drainage, and postoperative inflammatory markers compared to the MIS-TLIF group (P < 0.05), but the AUSS-TLIF group had a significantly longer operative time compared to the MIS-TLIF group (P < 0.05).

CONCLUSION

Both AUSS-TLIF and MIS-TLIF achieve good clinical outcomes, but AUSS-TLIF, as an endoscopic surgery with an open surgical concept, offers advantages including greater flexibility, smaller trauma, less blood loss, shorter operative time, and shorter hospital stay. It provides a better perioperative experience for patients.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cd2/11980218/5a65eb867294/13018_2025_5779_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cd2/11980218/3659c0ad91a9/13018_2025_5779_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cd2/11980218/5a65eb867294/13018_2025_5779_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cd2/11980218/3659c0ad91a9/13018_2025_5779_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8cd2/11980218/5a65eb867294/13018_2025_5779_Fig1_HTML.jpg
摘要

目的

探讨关节镜辅助下单通道脊柱手术(AUSS)-经椎间孔腰椎椎间融合术(TLIF)治疗退变性腰椎管狭窄症(LSS)的临床疗效及优势。

方法

本研究纳入2022年1月至2023年12月在西安医学院第二附属医院脊柱外科接受手术治疗的71例腰椎管狭窄症患者。其中,34例行AUSS-TLIF手术,37例行微创TLIF(MIS-TLIF)手术。比较并分析AUSS-TLIF组和MIS-TLIF组术前及术后的视觉模拟评分(VAS)下腰痛和腿痛评分、Oswestry功能障碍指数(ODI)评分、椎间盘高度、椎管前后径(APDC)、手术相关参数(如手术时间、术中出血量、术后引流量、术后C反应蛋白水平及住院时间)及手术效果。

结果

71例患者均获随访。AUSS-TLIF组与MIS-TLIF组术前VAS评分或ODI指数差异无统计学意义(P>0.05)。术后3天,两组腰腿痛症状均明显减轻,VAS评分均显著低于术前(P<0.05)。然而,AUSS-TLIF组术后3天及3个月时VAS评分低于MIS-TLIF组,差异有统计学意义(P<0.05)。术后12个月,两组VAS评分差异无统计学意义(P>0.05)。两组术后3个月及12个月腰椎功能均明显改善,ODI评分均显著低于术前(P<0.05)。然而,AUSS-TLIF组术后3个月ODI评分低于MIS-TLIF组,差异有统计学意义(P<0.05),术后12个月差异无统计学意义(P>0.05)。两组术前椎间盘高度及APDC差异无统计学意义(P>0.05)。术后12个月CT扫描显示,两组椎间盘高度及APDC均较术前明显增加(P<0.05),组间差异无统计学意义(P>0.05)。AUSS-TLIF组手术出血量、术后引流量及术后炎症指标低于MIS-TLIF组(P<0.05),但AUSS-TLIF组手术时间显著长于MIS-TLIF组(P<0.05)。

结论

AUSS-TLIF和MIS-TLIF均取得了良好的临床效果,但AUSS-TLIF作为一种具有开放手术理念的内镜手术,具有更大的灵活性、更小的创伤、更少的出血、更短的手术时间和住院时间等优势,为患者提供了更好的围手术期体验。

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