Kisely Steve, Siskind Dan, Speyer Helene
School of Medicine, The University of Queensland, Brisbane, QLD, Australia.
Metro South Addiction and Mental Health Service, Woolloongabba, QLD, Australia.
BJPsych Open. 2025 Apr 10;11(3):e85. doi: 10.1192/bjo.2025.34.
Obesity is a major health problem among people with severe mental illness, linked to increased risk of chronic diseases and reduced life expectancy. This is attributable to a combination of factors, including lifestyle, social circumstances, medication side-effects and the illness itself. Second-generation antipsychotics are particularly associated with weight gain, affecting treatment adherence, symptoms and quality of life.
肥胖是重度精神疾病患者中的一个主要健康问题,与慢性病风险增加和预期寿命缩短有关。这可归因于多种因素的综合作用,包括生活方式、社会环境、药物副作用和疾病本身。第二代抗精神病药物尤其与体重增加有关,会影响治疗依从性、症状和生活质量。