Effect of pentagastrin infusion on gastroesophageal manometry and reflux status before and after esophagogastrectomy.

The lower esophageal high pressure zone of eight Rhesus monkeys was characterized by manometry and reflux testing. It was found to respond characteristically to pentagastrin infusions. After excision of the lower esophageal segment and tis replacement by a stomach tube, an apparently normal, functional high pressure zone was demonstrable within the substitute.