Lawson Schuyler C, Kasza Karin, Collins R Lorraine, O'Connor Richard J, Homish Gregory G
Burton Blatt Institute, Syracuse University, USA.
Department of Health Behavior, Roswell Park Comprehensive Cancer Center, USA.
Addict Behav. 2025 Aug;167:108354. doi: 10.1016/j.addbeh.2025.108354. Epub 2025 Apr 9.
Most individuals who smoke cigarettes are interested in quitting, but many are unable to quit. Fewer than one-third of individuals who smoke cigarettes attempt to quit using FDA-approved cessation methods, such as nicotine replacement therapy (NRT) and prescription medications. Smoking cessation apps (SCAs) provide individuals with personalized quit plans, information about smoking cessation treatments, craving management strategies, and other features. However, their relationship to NRT/prescription medication utilization and quit attempts is understudied.
We conducted a longitudinal secondary data analysis using a subset of adults who smoked at least 100 cigarettes in their lifetime, currently smoked every day or some days, and planned to quit within a year. This subset was drawn from the Population Assessment of Tobacco and Health (PATH) Study, a nationally representative cohort study. We utilized Generalizing Estimating Equation models to examine the longitudinal associations between SCA use initiation and the following outcomes across 2014-2019: NRT, prescription medications, and quit attempts.
SCA use initiation was associated with greater odds of prescription medication utilization (AOR = 2.43, 95 % CI: 1.63, 3.64; p < 0.05). Likewise, SCA use initiation was associated with greater odds of making a quit attempt (AOR = 1.38, 95 % CI: 1.09, 1.76; p < 0.01), but not NRT utilization.
Among adults who regularly smoked cigarettes and had plans to quit, SCA use initiation was associated with prescription medication utilization and quit attempts but not NRT utilization. SCAs may have utility as a population-level intervention but specific features needed to be studied further.
SCA, Smoking Cessation App; NRT, Nicotine Replacement Therapy.
大多数吸烟的人都有戒烟的意愿，但很多人无法成功戒烟。尝试使用美国食品药品监督管理局（FDA）批准的戒烟方法（如尼古丁替代疗法（NRT）和处方药）来戒烟的吸烟者不到三分之一。戒烟应用程序（SCA）为用户提供个性化的戒烟计划、戒烟治疗信息、渴望管理策略及其他功能。然而，它们与NRT/处方药使用及戒烟尝试之间的关系尚未得到充分研究。
我们使用了纵向二次数据分析，研究对象为一生中至少吸过100支烟、目前每天或偶尔吸烟且计划在一年内戒烟的成年人子集。该子集取自全国代表性队列研究“烟草与健康人口评估（PATH）研究”。我们使用广义估计方程模型来研究2014 - 2019年间SCA使用起始与以下结果之间的纵向关联：NRT、处方药和戒烟尝试。
开始使用SCA与使用处方药的几率更高相关（调整后比值比[AOR]=2.43，95%置信区间[CI]：1.63，3.64；p<0.05）。同样，开始使用SCA与进行戒烟尝试的几率更高相关（AOR = 1.38，95% CI：1.09，1.76；p<0.01），但与NRT使用无关。
在经常吸烟且有戒烟计划的成年人中，开始使用SCA与处方药使用及戒烟尝试相关，但与NRT使用无关。SCA作为一种人群层面的干预措施可能具有实用价值，但具体特征还需要进一步研究。
SCA，戒烟应用程序；NRT，尼古丁替代疗法
