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比卡鲁胺综述

Bicalutamide: A review.

作者信息

Aulakh Shayna, Mysore Venkataram

机构信息

Department of Dermatology, Venkat Charmalaya - Centre for PG training and Advanced Dermatology, Affiliated to Rajiv Gandhi University of Health Sciences, Bangalore, Karnataka, India.

出版信息

J Cutan Aesthet Surg. 2025 Apr-Jun;18(2):78-85. doi: 10.25259/jcas_182_23. Epub 2024 Sep 6.

Abstract

Bicalutamide is a non-steroidal androgen receptor antagonist that exerts anti-androgenic effects on peripheral tissues. It has been recently of interest in female pattern hair loss and has led to the off-label use of this drug for the improvement of Sinclair grading in such patients. This review aims to discuss the pharmacological properties along with indications, contraindications, and safety profile of bicalutamide for its use in dermatological research.

摘要

比卡鲁胺是一种非甾体类雄激素受体拮抗剂,对周围组织发挥抗雄激素作用。它最近在女性型脱发方面受到关注,并导致该药物被用于改善此类患者的辛克莱分级,但属于超说明书用药。本综述旨在讨论比卡鲁胺在皮肤病学研究中的药理特性以及适应证、禁忌证和安全性概况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6305/11980709/0b9613e7bc69/JCAS-18-078-g001.jpg

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