Yu Guangbo, Qu Aihua, Wu Zhimeng, Xu Liguang, Xu Chuanlai, Kuang Hua
International Joint Research Laboratory for Biointerface and Biodetection State Key Lab of Food Science and Technology School of Food Science and Technology Wuxi Jiangsu 214122 PRC.
The Key Laboratory of Carbohydrate Chemistry & Biotechnology Ministry of Education School of Biotechnology Jiangnan University Wuxi Jiangsu 214122 PRC.
Small Sci. 2023 Nov 27;4(1):2300123. doi: 10.1002/smsc.202300123. eCollection 2024 Jan.
Chirality is a common occurrence in nature and forms a critical basis for life. The unique optical activity of chiral nanomaterials plays an important role in the nanobiology field, particularly in the regulation of reactive oxygen species (ROS), both in cells and in vivo. By regulating ROS, chiral nanomaterials can achieve numerous biological effects. Herein, progression in the application of chiral nanomaterials in the field of bioscience is introduced. First, the strategies used to construct different types of ROS-related chiral nanomaterials are introduced. Then, the biological effects that can be achieved using chiral nanomaterials to regulate ROS are reviewed. Finally, the key issues and future prospects of chiral nanomaterials in the regulation of ROS are discussed.
手性在自然界中普遍存在,是生命的关键基础。手性纳米材料独特的光学活性在纳米生物学领域发挥着重要作用,特别是在细胞和体内对活性氧(ROS)的调控方面。通过调控ROS,手性纳米材料可以实现多种生物学效应。本文介绍了手性纳米材料在生物科学领域的应用进展。首先,介绍了构建不同类型ROS相关手性纳米材料所采用的策略。然后,综述了利用手性纳米材料调控ROS可实现的生物学效应。最后,讨论了手性纳米材料在ROS调控方面的关键问题和未来前景。