• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Systematic pan-cancer analysis identifies DNASE2 as a potential prognostic marker and immunotherapeutic target for glioblastoma multiforme.

作者信息

Cao Jun, Chen Si, An Ping, Wang Xingqiang, Xiao Xinru, Li Shichao, Cheng Ye

机构信息

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Department of Neurosurgery, Affiliated Ri Zhao People's Hospital, Jining Medical College, Rizhao, Shandong 276826, China.

出版信息

Genes Dis. 2024 Sep 10;12(4):101431. doi: 10.1016/j.gendis.2024.101431. eCollection 2025 Jul.

DOI:10.1016/j.gendis.2024.101431
PMID:40212796
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11984583/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/a1f95edaf90a/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/0361cd0ecd82/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/48446bc58466/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/fbac0f3dcc05/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/e925b84be47a/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/a1f95edaf90a/figs4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/0361cd0ecd82/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/48446bc58466/figs1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/fbac0f3dcc05/figs2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/e925b84be47a/figs3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5820/11984583/a1f95edaf90a/figs4.jpg

相似文献

1
Systematic pan-cancer analysis identifies DNASE2 as a potential prognostic marker and immunotherapeutic target for glioblastoma multiforme.全癌系统分析确定DNASE2为多形性胶质母细胞瘤的潜在预后标志物和免疫治疗靶点。
Genes Dis. 2024 Sep 10;12(4):101431. doi: 10.1016/j.gendis.2024.101431. eCollection 2025 Jul.
2
A Pan-Cancer Analysis of Transcriptome and Survival Reveals Prognostic Differentially Expressed LncRNAs and Predicts Novel Drugs for Glioblastoma Multiforme Therapy.一项转录组与生存情况的泛癌分析揭示了预后差异表达的长链非编码RNA,并预测了多形性胶质母细胞瘤治疗的新型药物。
Front Genet. 2021 Aug 24;12:723725. doi: 10.3389/fgene.2021.723725. eCollection 2021.
3
TSPAN4 is a prognostic and immune target in Glioblastoma multiforme.四跨膜蛋白4(TSPAN4)是多形性胶质母细胞瘤的一个预后和免疫靶点。
Front Mol Biosci. 2023 Jan 6;9:1030057. doi: 10.3389/fmolb.2022.1030057. eCollection 2022.
4
Comprehensive Pan-Cancer Analysis of GINS2 for Human Tumour Prognosis and as an Immunological Biomarker.全面泛癌分析 GINS2 对人类肿瘤预后的影响及其作为免疫生物标志物的作用。
Comput Math Methods Med. 2022 Nov 23;2022:3119721. doi: 10.1155/2022/3119721. eCollection 2022.
5
Pan-cancer analysis of the role of α2C-adrenergic receptor (ADRA2C) in human tumors and validation in glioblastoma multiforme models.α2C肾上腺素能受体(ADRA2C)在人类肿瘤中的泛癌分析及在多形性胶质母细胞瘤模型中的验证
J Cancer. 2024 Sep 9;15(17):5691-5709. doi: 10.7150/jca.98240. eCollection 2024.
6
Immune profiling of human tumors identifies CD73 as a combinatorial target in glioblastoma.人类肿瘤的免疫分析鉴定 CD73 为胶质母细胞瘤的组合靶标。
Nat Med. 2020 Jan;26(1):39-46. doi: 10.1038/s41591-019-0694-x. Epub 2019 Dec 23.
7
The prognostic effect of neutrophil-to-lymphocyte ratio and De Ritis ratio in glioblastoma multiforme patients.中性粒细胞与淋巴细胞比值和 De Ritis 比值在多形性胶质母细胞瘤患者中的预后影响。
Bratisl Lek Listy. 2024;125(8):463-467. doi: 10.4149/BLL_2024_71.
8
Pan-cancer analysis identifies RNF43 as a prognostic, therapeutic and immunological biomarker.泛癌症分析鉴定 RNF43 为一种预后、治疗和免疫生物标志物。
Eur J Med Res. 2023 Oct 17;28(1):438. doi: 10.1186/s40001-023-01383-1.
9
Pan-cancer analysis of ASB3 and the potential clinical implications for immune microenvironment of glioblastoma multiforme.多癌种分析 ASB3 与胶质母细胞瘤多形性的免疫微环境的潜在临床意义。
Front Immunol. 2022 Dec 21;13:842524. doi: 10.3389/fimmu.2022.842524. eCollection 2022.
10
Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma.基于铜死亡相关基因的系统分析鉴定出铁氧还蛋白 1 是胶质母细胞瘤的免疫调节剂和治疗靶点。
BMC Cancer. 2023 Dec 19;23(1):1249. doi: 10.1186/s12885-023-11727-z.

引用本文的文献

1
Acasunlimab, an Fc-inert PD-L1×4-1BB bispecific antibody, combined with PD-1 blockade potentiates antitumor immunity via complementary immune modulatory effects.阿卡萨单抗(Acasunlimab)是一种Fc惰性的PD-L1×4-1BB双特异性抗体,与PD-1阻断剂联合使用可通过互补的免疫调节作用增强抗肿瘤免疫力。
J Immunother Cancer. 2025 Apr 10;13(4):e011377. doi: 10.1136/jitc-2024-011377.

本文引用的文献

1
Optimal cancer evasion in a dynamic immune microenvironment generates diverse post-escape tumor antigenicity profiles.在动态免疫微环境中实现最佳的癌症逃逸会产生多样化的逃逸后肿瘤抗原性特征。
Elife. 2023 Apr 25;12:e82786. doi: 10.7554/eLife.82786.
2
Lipophagy-related gene RAB7A is involved in immune regulation and malignant progression in hepatocellular carcinoma.自噬相关基因RAB7A参与肝细胞癌的免疫调节和恶性进展。
Comput Biol Med. 2023 May;158:106862. doi: 10.1016/j.compbiomed.2023.106862. Epub 2023 Apr 6.
3
Circ_0073228 serves as a competitive endogenous ribonucleic acid to facilitate proliferation and inhibit apoptosis of hepatocellular carcinoma cells by the miR-139-5p/deoxyribonuclease II axis.
Circ_0073228 作为竞争性内源性 RNA,通过 miR-139-5p/脱氧核糖核酸酶 II 轴促进肝癌细胞的增殖并抑制其凋亡。
J Gene Med. 2023 Aug;25(8):e3507. doi: 10.1002/jgm.3507. Epub 2023 Apr 17.
4
High endothelial venules proportion in tertiary lymphoid structure is a prognostic marker and correlated with anti-tumor immune microenvironment in colorectal cancer.三级淋巴结构中的高内皮静脉比例是结直肠癌的预后标志物,并与抗肿瘤免疫微环境相关。
Ann Med. 2023 Dec;55(1):114-126. doi: 10.1080/07853890.2022.2153911.
5
Dnases in health and disease.健康与疾病中的脱氧核糖核酸酶
Dev Biol. 2017 Sep 1;429(1):1-11. doi: 10.1016/j.ydbio.2017.06.028. Epub 2017 Jun 28.