Hand Catherine, Bohn Camden, Gornbein Chase, Khazi-Syed Daanish, Chang Josh, Savoia Andrew, Forsythe Brian
Rush University Medical Center, Chicago, IL, USA.
J Orthop. 2025 Mar 15;69:96-100. doi: 10.1016/j.jor.2025.03.032. eCollection 2025 Nov.
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by joint inflammation, pain, and stiffness, often progressing to joint erosion and deformity. Shoulder arthroplasty is a reliable treatment for alleviating severe arthritic pain in RA patients. This study examines the outcomes and complications of shoulder arthroplasty in individuals with RA.
A retrospective cohort study using the PearlDiver national insurance claims database identified patients over 18 who underwent primary shoulder arthroplasty, including anatomic, reverse, and hemiarthroplasty, between 2010 and 2020. Patients with preoperative RA were matched 1:2 with healthy controls by age and gender. Primary outcomes included revision arthroplasty and rotator cuff repair (RCR), while 90-day complications such as infections, wound disruption, and medical conditions were secondary outcomes. Statistical significance was assessed using multivariate and Chi-square analyses.
Of 33,282 patients, 11,431 (34.3 %) had preoperative RA. The RA group exhibited significantly higher rates of 90-day complications, including infections (OR 4.4, p < 0.001), ED visits (OR 3.0, p < 0.001), cardiac arrhythmias (OR 3.0, p = 0.015), deep vein thrombosis (OR 1.3, p = 0.045), and pulmonary embolism (OR 4.2, p < 0.001). However, no significant differences were observed in revision or RCR rates between groups.
Patients with RA undergoing shoulder arthroplasty face increased risks of postoperative complications compared to controls, highlighting the need for tailored perioperative strategies to optimize outcomes in this high-risk population.
类风湿性关节炎(RA)是一种慢性自身免疫性疾病,其特征为关节炎症、疼痛和僵硬,常发展为关节侵蚀和畸形。肩关节置换术是缓解RA患者严重关节炎疼痛的可靠治疗方法。本研究探讨了RA患者肩关节置换术的疗效和并发症。
一项回顾性队列研究使用PearlDiver国家保险理赔数据库,确定了2010年至2020年间接受初次肩关节置换术(包括解剖型、反置型和半关节置换术)的18岁以上患者。术前患有RA的患者按年龄和性别与健康对照进行1:2匹配。主要结局包括翻修置换术和肩袖修复术(RCR),而感染、伤口裂开和内科疾病等90天并发症为次要结局。使用多变量分析和卡方分析评估统计学显著性。
在33282例患者中,11431例(34.3%)术前患有RA。RA组90天并发症发生率显著更高,包括感染(比值比4.4,p<0.001)、急诊就诊(比值比3.0,p<0.001)、心律失常(比值比3.0,p=0.015)、深静脉血栓形成(比值比1.3,p=0.045)和肺栓塞(比值比4.2,p<0.001)。然而,两组之间在翻修率或RCR率方面未观察到显著差异。
与对照组相比,接受肩关节置换术的RA患者术后并发症风险增加,这突出表明需要制定针对性的围手术期策略,以优化这一高危人群的治疗效果。