Alkeraithe Fawaz, Alghtani Yazeed, Abo Rubeea Subhy, Alkhalifah Mutasim, Alenzi Majed, Alhussain Abdulaziz
Department of Urology, King Fahad Medical City, Riyadh, Saudi Arabia.
College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Urol Case Rep. 2025 Mar 18;60:103013. doi: 10.1016/j.eucr.2025.103013. eCollection 2025 May.
Lipoblastomas are rare benign tumors arising from embryonal fat tissues, commonly occurring in early childhood. Scrotal presentation is exceedingly rare, with 18 cases reported in the literature. We present a 2-year-old male with a 5-month history of painless scrotal swelling, initially suspected of being malignant. Imaging suggested the possibility of atypical lipoma. The patient underwent orchiectomy. Histopathologic examination confirmed the diagnosis of lipoblastoma, with no MDM2 amplification. After two years of follow-up, the patient remains recurrence-free. This case highlights the challenges of diagnosing pediatric scrotal masses preoperatively and highlights the importance of a multidisciplinary approach for accurate diagnosis and management.
脂肪母细胞瘤是一种罕见的起源于胚胎脂肪组织的良性肿瘤，常见于儿童早期。阴囊脂肪母细胞瘤极为罕见，文献中仅报道过18例。我们报告一例2岁男性患儿，有5个月无痛性阴囊肿胀病史，最初怀疑为恶性肿瘤。影像学检查提示非典型脂肪瘤的可能性。该患者接受了睾丸切除术。组织病理学检查确诊为脂肪母细胞瘤，无MDM2基因扩增。经过两年的随访，患者无复发。该病例凸显了小儿阴囊肿块术前诊断的挑战，并强调了多学科方法对于准确诊断和管理的重要性。
