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资源有限环境下一名两岁也门女童的幼年皮肌炎:病例报告

Juvenile Dermatomyositis in a Two-Year-Old Yemeni Girl in a Resource-Limited Setting: A Case Report.

作者信息

Omer Bin-Sahel, Abduljabbar Naif, Kutbi Mohammed S, Bani Ahmed S, Saghir Mohammed A

机构信息

Medicine and Surgery, Faculty of Medicine and Health Sciences, Seiyun University, Seiyun, YEM.

Community Health Nursing, Faculty of Nursing, University of Khartoum, Khartoum, SDN.

出版信息

Cureus. 2025 Mar 10;17(3):e80376. doi: 10.7759/cureus.80376. eCollection 2025 Mar.

Abstract

Juvenile dermatomyositis (JDM) is a rare systemic autoimmune vasculopathy primarily affecting children. It is characterized by muscular weakness and distinctive skin findings. This report describes the case of a two-year-old Yemeni girl from a resource-limited setting who presented with prolonged fever and later developed classic JDM symptoms, including malar rash, skin nodules, calcifications, and lower limb muscle weakness. Despite the unavailability of advanced diagnostic tools, the diagnosis was made based on clinical findings, elevated inflammatory markers, and muscle enzyme levels. Management included oral prednisolone, resulting in significant clinical improvement. This case highlights the challenges of diagnosing and managing atypical JDM presentations in resource-constrained areas while emphasizing the importance of clinical vigilance and multidisciplinary care. It also underscores the need for increasing awareness and better diagnostic access in low-resource settings. To our knowledge, this is the first reported case of JDM in Yemen.

摘要

幼年皮肌炎(JDM)是一种罕见的主要影响儿童的系统性自身免疫性血管病。其特征为肌肉无力和独特的皮肤表现。本报告描述了一名来自资源有限地区的两岁也门女孩的病例,她起初持续发热,随后出现了典型的JDM症状,包括颧部皮疹、皮肤结节、钙化和下肢肌肉无力。尽管缺乏先进的诊断工具,但根据临床发现、炎症标志物升高和肌肉酶水平做出了诊断。治疗包括口服泼尼松龙,临床症状得到显著改善。该病例突出了在资源有限地区诊断和管理非典型JDM表现的挑战,同时强调了临床警惕性和多学科护理的重要性。它还强调了在资源匮乏地区提高认识和改善诊断途径的必要性。据我们所知,这是也门首例报告的JDM病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a362/11982588/520c158b37b6/cureus-0017-00000080376-i01.jpg

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