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纳米颗粒作为调节宿主对牙周炎治疗反应的策略。

Nanoparticles as Strategies for Modulating the Host's Response in Periodontitis Treatment.

作者信息

Mlachkova Antoaneta, Dosseva-Panova Velitchka, Maynalovska Hristina, Pashova-Tasseva Zdravka

机构信息

Department of Periodontology, Faculty of Dental Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.

出版信息

Nanomaterials (Basel). 2025 Mar 21;15(7):476. doi: 10.3390/nano15070476.

Abstract

Periodontitis is a widespread disease, associated with challenges both in its diagnosis and in selecting from various therapeutic approaches, which do not always yield the expected success. This literature review was conducted to explore diverse therapeutic approaches, especially those focused on nanotechnologies, and their potential contribution to the successful modulation of the host's response. The effects of the existing microbial diversity and the imbalance of key microbial species in contributing to the progression and worsening of the host's response in periodontitis are well known. It is essential to understand the role of a well-structured treatment plan for periodontitis, providing opportunities for new research and innovative treatment strategies aimed at reducing the impact of periodontitis on oral and overall systemic health. This will be beneficial for dental professionals, enabling them to effectively prevent and treat periodontitis, ultimately improving the overall health and well-being of patients.

摘要

牙周炎是一种广泛流行的疾病,在其诊断以及从各种治疗方法中进行选择方面都面临挑战,而这些治疗方法并不总能取得预期的成功。进行这项文献综述是为了探索多种治疗方法,特别是那些专注于纳米技术的方法,以及它们对成功调节宿主反应的潜在贡献。现有微生物多样性以及关键微生物种类失衡在导致牙周炎中宿主反应的进展和恶化方面所起的作用是众所周知的。了解针对牙周炎的结构合理的治疗计划的作用至关重要,这为旨在减少牙周炎对口腔和整体全身健康影响的新研究和创新治疗策略提供了机会。这将对牙科专业人员有益,使他们能够有效地预防和治疗牙周炎,最终改善患者的整体健康和福祉。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4cc/11990483/0f06abfaa486/nanomaterials-15-00476-g001.jpg

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