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机器人辅助全膝关节置换术降低了多种骨科并发症的中期发生率:一项大型数据库研究。

Robotic-assisted total knee arthroplasty reduced mid-term incidences of multiple orthopaedic complications: A large database study.

作者信息

Wainwright Jared D, Gay Samuel S, Ou Joshua T, Nguyen Adam, Barimani Bardia, Wenke Joseph C

机构信息

Department of Orthopaedic Surgery and Rehabilitation, The University of Texas Medical Branch at Galveston, Galveston, USA.

Shriners Hospitals for Children - Galveston, Galveston, USA.

出版信息

Arch Orthop Trauma Surg. 2025 Apr 11;145(1):235. doi: 10.1007/s00402-025-05856-2.

Abstract

BACKGROUND

Robotic-assisted total knee arthroplasty (rTKA) provides surgeons the ability to make more accurate bone cuts and reduce outliers associated with conventional, jig-based total knee arthroplasty (cTKA). Despite its increase in popularity there continues to be insufficient data showing an improvement in mid-term patient outcomes.

MATERIALS AND METHODS

The TriNetX Research Database was retrospectively queried for patients undergoing primary TKA with a follow up of at least 5 years after index surgery. Patient records with surgeries performed between January 1, 2012, to December 31, 2019. Records with comorbid indications other than primary TKA were excluded such as distal femur fractures, pathologic fractures, or revision arthroplasty. Propensity score matching at one-to-one ratio was performed to reduce confounding of preoperative risks. Outcomes of aseptic loosening, prosthetic joint infection, instability, periprosthetic fracture, and revision were queried at 1, 3, and 5 years.

RESULTS

In this study, 141,613 patients met all study eligibility requirements with 129,622 patients and 11,991 patients in the cTKA and rTKA cohorts, respectively. At 5 years, patients in the rTKA cohort had lower incidence of aseptic loosening (OR 0.335, 95% CI 0.224-0.501), prosthetic joint infection (OR 0.529, 95% CI 0.417-0.672), revisions (OR 0.758, 95% CI 0.609-0.943), and all complications combined (OR 0.640, 95% CI 0.550-0.745).

CONCLUSIONS

Robotic TKA was found to be associated with a reduction in aseptic loosening, prosthetic joint infections, revisions, and all complications combined. This improvement in mid-term patient outcomes is observed at multiple time points out to 5 years, both before and after propensity score matching.

摘要

背景

机器人辅助全膝关节置换术(rTKA)使外科医生能够进行更精确的截骨,并减少与传统的基于夹具的全膝关节置换术(cTKA)相关的异常情况。尽管其受欢迎程度不断提高,但仍缺乏足够的数据表明中期患者预后有所改善。

材料与方法

对TriNetX研究数据库进行回顾性查询,以获取接受初次全膝关节置换术且在初次手术后至少随访5年的患者。查询2012年1月1日至2019年12月31日期间进行手术的患者记录。排除除初次全膝关节置换术以外有合并症指征的记录,如股骨远端骨折、病理性骨折或翻修关节成形术。以一对一的比例进行倾向评分匹配,以减少术前风险的混杂因素。在1年、3年和5年时查询无菌性松动、人工关节感染、不稳定、假体周围骨折和翻修的结果。

结果

在本研究中,141,613名患者符合所有研究资格要求,其中cTKA队列中有129,622名患者,rTKA队列中有11,991名患者。在5年时,rTKA队列中的患者无菌性松动(OR 0.335,95% CI 0.224 - 0.501)、人工关节感染(OR 0.529,95% CI 0.417 - 0.672)、翻修(OR 0.758,95% CI 0.609 - 0.943)以及所有并发症合并发生率(OR 0.640,95% CI 0.550 - 0.745)均较低。

结论

发现机器人全膝关节置换术与无菌性松动、人工关节感染、翻修以及所有并发症合并发生率的降低相关。在倾向评分匹配前后的5年多个时间点均观察到中期患者预后的这种改善。

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