David Eytan A, Shahnaz Navid
Otology, Neurotology, Skull Base Surgery, Clinical Instructor, Department of Surgery, University of British Columbia, Vancouver, Canada.
Audiology and Speech Sciences, University of British Columbia, Vancouver, Canada.
J Neuroeng Rehabil. 2025 Apr 11;22(1):81. doi: 10.1186/s12984-025-01608-w.
Vestibular deficits are common and debilitating. Many patients do not achieve satisfactory resolution of their symptoms with standard rehabilitation techniques. This study seeks to measure changes in computerized dynamic posturography sensory ratio information after computerized vestibular retraining therapy (CVRT).
This prospective, single group, interventional study enrolled adult participants with stable, unilateral vestibular deficits. Before and after twelve twice weekly sessions of CVRT, and 4-6 and 10-12 months post-treatment, participants completed the Sensory Organization Test, from which sensory ratios (somatosensory - SOM, visual - VIS, vestibular - VEST, and visual preference - PREF) were calculated.
13 participants completed the intervention and post-retraining assessment; 9 completed the 4-6 and 10-12 month assessments. After CVRT, VIS increased by 11.6 (1.6 to 21.7) and VEST increased by 9.5 (0.6 to 18.3) and both remained significantly above baseline 10-12 months after treatment. The SOM and PREF ratios changed negligibly. Participants with mild disability (DHI ≤ 30) showed no change while participants with moderate-to-severe disability (DHI > 30) had significantly greater improvements in VIS (P = 0.0006) and VEST (P = 0.02) across all three post-treatment assessments.
CVRT was associated with durable improvement in VIS and VEST sensory ratios and improved postural control under conditions that favour use of vestibular information, consistent with increased weighting of vestibular information over vision.
Clinicaltrials.gov registration NCT04875013; 04/27/2021.
前庭功能障碍很常见且使人衰弱。许多患者采用标准康复技术后症状未得到满意缓解。本研究旨在测量计算机化前庭再训练疗法（CVRT）后计算机化动态姿势描记术感觉比率信息的变化。
这项前瞻性、单组、干预性研究纳入了患有稳定单侧前庭功能障碍的成年参与者。在进行12次每周两次的CVRT治疗前和治疗后，以及治疗后4 - 6个月和10 - 12个月，参与者完成感觉组织测试，从中计算感觉比率（躯体感觉 - SOM、视觉 - VIS、前庭 - VEST和视觉偏好 - PREF）。
13名参与者完成了干预和训练后评估；9名完成了4 - 6个月和10 - 12个月的评估。CVRT治疗后，VIS增加了11.6（从1.6增至21.7），VEST增加了9.5（从0.6增至18.3），且在治疗后10 - 12个月两者均显著高于基线水平。SOM和PREF比率变化可忽略不计。轻度残疾（残疾评定量表DHI≤30）的参与者无变化，而中度至重度残疾（DHI>30）的参与者在所有三次治疗后评估中VIS（P = 0.0006）和VEST（P = 0.02）有显著更大改善。
CVRT与VIS和VEST感觉比率的持久改善相关，并在有利于使用前庭信息的条件下改善了姿势控制，这与前庭信息相对于视觉增加的权重一致。
Clinicaltrials.gov注册编号NCT04875013；2021年4月27日。
