Parker R G
Cancer. 1977 Feb;39(2 Suppl):802-5. doi: 10.1002/1097-0142(197702)39:2+<802::aid-cncr2820390714>3.0.co;2-b.
Radiation therapy with "heavy" particles offers potential biological and physical advantages compared to irradiation with low LET photons. Clinical studies are in progress with proton beams, which have dosimetric advantages, and fast neutron beams, which have potential biologic advantages. Clinical studies with negative pi mesons and heavy nuclei, which have combined dosimetric and biologic advantages are about to start.
与低传能线密度光子照射相比,“重”粒子放射治疗具有潜在的生物学和物理学优势。目前正在进行质子束临床研究,质子束具有剂量学优势;还有快中子束临床研究,快中子束具有潜在生物学优势。具有剂量学和生物学综合优势的负π介子和重原子核的临床研究即将开展。