Zhang Weng-Dong, Ma Bin, Qi Ping-An, Wang Gang, Su Xiao Rong, Ma Xiao Yun, Li Tian-Gang
Ultrasound Medicine Center, Gansu Provincial Maternity and Child-Care Hospital, Lanzhou, People's Republic of China.
BMC Pregnancy Childbirth. 2025 Apr 12;25(1):437. doi: 10.1186/s12884-025-07560-w.
Anomalous drainage of the ductus venosus (DV) into the coronary sinus (CS) is a rare fetal vascular anomaly that poses challenges for prenatal diagnosis. This study aimed to investigate the role of two-dimensional (2D) and three-dimensional (3D) ultrasound imaging, specifically spatiotemporal image correlation (STIC) technology, in improving the prenatal diagnosis of this anomaly.
We retrospectively reviewed eight cases of fetuses diagnosed with anomalous DV drainage into the CS at Gansu Provincial Maternal and Child Health Hospital between September 2019 and September 2024. The gestational age of the fetuses ranged from 24 to 30 weeks. Ultrasound examinations, including 2D and Doppler imaging, along with HDlive Flow combined with STIC technology, were used for diagnosis. Differential diagnoses were made based on imaging findings. Descriptive statistics were employed to summarize the results.
Eight fetuses with anomalous DV drainage into the CS were identified. Of these, five cases were isolated anomalies, while three had associated malformations, such as aberrant right subclavian artery and right aortic arch. Dilated CS was observed in all cases, with an average inner diameter of 5.7 mm. STIC imaging successfully visualized the abnormal course of the DV, enhancing diagnostic confidence. Postnatal follow-up indicated favorable outcomes for most neonates (except for Case NO.3 and Case NO.7), although persistent CS dilation was observed in these cases, without significant hemodynamic compromise or clinical symptoms.
Prenatal diagnosis of anomalous DV drainage into the CS can be effectively achieved using 2D and 3D ultrasound, with STIC technology providing added diagnostic clarity. Early and accurate detection is crucial for ensuring appropriate clinical management and favorable outcomes. Ongoing surveillance of CS dilation in the postnatal period is recommended.
静脉导管（DV）异常引流至冠状窦（CS）是一种罕见的胎儿血管异常，对产前诊断构成挑战。本研究旨在探讨二维（2D）和三维（3D）超声成像，特别是时空图像相关（STIC）技术在改善这种异常的产前诊断中的作用。
我们回顾性分析了2019年9月至2024年9月在甘肃省妇幼保健院诊断为DV异常引流至CS的8例胎儿。胎儿的孕周为24至30周。超声检查，包括2D和多普勒成像，以及HDlive Flow联合STIC技术用于诊断。根据影像学表现进行鉴别诊断。采用描述性统计来总结结果。
确定了8例DV异常引流至CS的胎儿。其中，5例为孤立性异常，3例伴有其他畸形，如右锁骨下动脉异常和右主动脉弓。所有病例均观察到CS扩张，平均内径为5.7毫米。STIC成像成功显示了DV的异常走行，增强了诊断信心。产后随访表明，大多数新生儿预后良好（3号病例和7号病例除外），尽管这些病例中观察到CS持续扩张，但无明显血流动力学损害或临床症状。
使用2D和3D超声可以有效实现DV异常引流至CS的产前诊断，STIC技术提供了额外的诊断清晰度。早期准确检测对于确保适当的临床管理和良好预后至关重要。建议在产后对CS扩张进行持续监测。
