伊朗老年人握力和步速与认知障碍的关系：比尔詹德纵向衰老研究

Handgrip strength and gait speed relationships with cognitive impairment in Iranian older adults: Birjand longitudinal aging study.

作者信息

Nikkhah Amirabbas, Fakhrzadeh Hossein, Moodi Mitra, Khodabakhshi Huriye, Khorashadizadeh Masoumeh, Arzaghi Seyed Masoud, Varmaghani Mehdi, Ejtahed Hanieh-Sadat, Sharifi Farshad

机构信息

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran; Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Elderly Health Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Geriatr Nurs. 2025 May-Jun;63:280-287. doi: 10.1016/j.gerinurse.2025.03.052. Epub 2025 Apr 12.

DOI:10.1016/j.gerinurse.2025.03.052

PMID:40222209

Abstract

BACKGROUND

Cognitive impairment prevalence is rising with population aging. This study examined the relationship between handgrip strength and gait speed with cognitive impairment and performance in older adults.

METHODS

This cross-sectional study used baseline data from Birjand Longitudinal Aging Study (BLAS), including 1347 older adults. Cognitive function was evaluated using the six-item Cognitive Impairment Test (6-CIT). Gait speed was measured over six meters, and grip strength was assessed with hand dynamometers.

RESULTS

After adjusting for potential confounders, the association between low handgrip strength and cognitive impairment lost its significance (relative risk ratio (RRR) = 1.07, 95% CI: 0.70, 1.63). However, low gait speed remained significantly associated with dementia (RRR = 1.92, 95% CI: 1.23, 3.01) after adjusting for age, sex, education, body mass index (BMI), hypertension, and depressive symptoms.

CONCLUSION

Low gait speed is significantly associated with dementia, highlighting the importance of incorporating physical function measures into dementia risk assessments.

摘要

背景

随着人口老龄化，认知障碍的患病率正在上升。本研究探讨了老年人握力和步速与认知障碍及表现之间的关系。

方法

这项横断面研究使用了比尔詹德纵向衰老研究（BLAS）的基线数据，包括1347名老年人。使用六项认知障碍测试（6-CIT）评估认知功能。在六米的距离内测量步速，并用握力计评估握力。

结果

在对潜在混杂因素进行调整后，低握力与认知障碍之间的关联失去了显著性（相对风险比（RRR）=1.07，95%置信区间：0.70，1.63）。然而，在对年龄、性别、教育程度、体重指数（BMI）、高血压和抑郁症状进行调整后，低步速仍与痴呆症显著相关（RRR = 1.92，95%置信区间：1.23，3.01）。