Rossi E, Ferraccioli G F, Cavalieri F, Menta R, Dall'Aglio P P, Migone L
Nephron. 1985;40(4):491-3. doi: 10.1159/000183528.
2 cases of acute renal failure associated with diclofenac therapy are reported. In the 1st case no other risk factors but diclofenac administration were identified. Renal biopsy showed patchy interstitial infiltration of mononuclear cells and polymorphonuclear leukocytes. In the 2nd case preexisting nephropathy and heart failure were underlying illnesses. In both cases renal function returned to the basal values after stopping the drug.
报告了2例与双氯芬酸治疗相关的急性肾衰竭病例。在第1例中，除了使用双氯芬酸外，未发现其他风险因素。肾活检显示单核细胞和多形核白细胞的斑片状间质浸润。在第2例中，先前存在的肾病和心力衰竭是基础疾病。在这两例中，停药后肾功能均恢复至基础值。
