Henley Stacy, Johnson Luke, Strickley John
University of Louisville School of Medicine, Louisville, Kentucky, USA.
Division of Dermatology, West Virginia University, Morgantown, West Virginia, USA.
Nutr Clin Pract. 2025 Jun;40(3):748-751. doi: 10.1002/ncp.11286. Epub 2025 Apr 13.
Scurvy, the clinical manifestation of vitamin C deficiency, exhibits the characteristic cutaneous findings of perifollicular petechiae, corkscrew hairs, gingivitis, swollen gums, and easy bruising. Syncope is a less reported presenting symptom. Although considered a rare nutritional deficiency not commonly seen in the developed world, it should remain on the differential for those with a history of malnutrition or malabsorption. We present a challenging and severe case of scurvy in a patient secondary to malnutrition and possible undiagnosed Crohn's disease. Recognizing classic dermatologic sequelae of scurvy-and potentially, less common symptoms such as syncope-can prompt diagnosis and treatment initiation.
坏血病是维生素C缺乏的临床表现，其特征性皮肤表现为毛囊周围瘀点、螺旋状毛发、牙龈炎、牙龈肿胀和易瘀伤。晕厥是较少报道的首发症状。尽管坏血病被认为是一种在发达国家不常见的罕见营养缺乏症，但对于有营养不良或吸收不良病史的患者，仍应将其列入鉴别诊断范围。我们报告了一例因营养不良和可能未确诊的克罗恩病继发坏血病的具有挑战性的严重病例。认识到坏血病的典型皮肤后遗症以及潜在的较少见症状（如晕厥），可促使进行诊断并开始治疗。
