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伴有弥漫性脑微出血的脑膜炎

Meningitis with Diffuse Cerebral Microhemorrhages.

作者信息

Sood Harleen, Gangadharappa Ramesha Chinakarihalli, Dey Rahul, Bhatia Vikas, Pannu Ashok Kumar

机构信息

Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Neurohospitalist. 2025 Apr 10:19418744251332982. doi: 10.1177/19418744251332982.

Abstract

is the leading cause of community-acquired bacterial meningitis across all age groups. Despite appropriate antibiotic therapy, the prognosis for pneumococcal meningitis remains poor. While common acute complications include cerebral edema, brain herniation, ventriculitis, hydrocephalus, and cerebral infarctions, hemorrhagic events are rarely reported. We present a case of a young male with meningitis, who developed diffuse cerebral microhemorrhages, an extremely rare complication. Despite culture-guided antibiotic therapy, the patient's condition deteriorated, requiring mechanical ventilation. Magnetic resonance imaging revealed diffuse cerebral microhemorrhages, prompting intensive supportive care. Prolonged mechanical support and a two-week antibiotic therapy led to gradual recovery, and the patient was discharged without neurological sequelae. This case highlights the importance of early imaging and timely intervention in managing rare complications of bacterial meningitis.

摘要

是所有年龄组社区获得性细菌性脑膜炎的主要病因。尽管进行了适当的抗生素治疗,肺炎球菌性脑膜炎的预后仍然很差。常见的急性并发症包括脑水肿、脑疝、脑室炎、脑积水和脑梗死,而出血事件很少被报道。我们报告一例患有脑膜炎的年轻男性病例,该患者发生了弥漫性脑微出血,这是一种极其罕见的并发症。尽管采用了培养指导下的抗生素治疗,但患者的病情仍恶化,需要机械通气。磁共振成像显示弥漫性脑微出血,促使进行强化支持治疗。长期的机械支持和为期两周的抗生素治疗导致病情逐渐恢复,患者出院时无神经后遗症。该病例强调了早期影像学检查和及时干预在处理细菌性脑膜炎罕见并发症中的重要性。

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Meningitis with Diffuse Cerebral Microhemorrhages.伴有弥漫性脑微出血的脑膜炎
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