Wang Jing, Li Wenjuan, Hu Yinghui, Lu Wanyu, Yu Xiao, Li Xiaofei, Zhang Daogong, Wang Haibo
Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital, Shandong University, Jinan, China.
Shandong Provincial Vertigo Dizziness Medical Center, Jinan, China.
Transl Pediatr. 2025 Mar 31;14(3):507-515. doi: 10.21037/tp-2025-128. Epub 2025 Mar 26.
Labyrinthitis ossificans (LO) is the end stage of labyrinthitis. Existing case reports primarily center around hearing loss and overlook a crucial aspect that patients with LO frequently experience balance problems, while our study fills this gap. We report a rare case of bilateral labyrinthitis secondary to meningitis with recurrent fluctuations in cochlear and vestibular symptoms over more than a decade, and incomplete ossification of the labyrinth.
An 8-month-old female patient was diagnosed with meningitis, and later experienced developmental delays and hearing issues. By 4-5 years, she had complete sensorineural hearing loss in the left ear. At 13 years, she started to experience problems in the right ear, such as hearing decline and aural fullness. Computed tomography and gadolinium-enhanced magnetic resonance imaging showed specific inner ear changes, and a decline in vestibular function. During the treatment course, the patient initially demonstrated an improvement in right - ear hearing. Nevertheless, her auditory function subsequently deteriorated, ultimately underwent cochlear implantation surgery. Fortunately, following the comprehensive treatment regimen, the patient's balance function recovered, and symptoms of dizziness ceased to recur.
This patient suffered from a rare form of labyrinthitis with fluctuating cochlear and vestibular symptoms over an extended course of illness. Despite the temporary effectiveness of corticosteroid treatment during the process, cochlear implantation was ultimately required. During the treatment, we paid special attention to the patient's vestibular function and observed a significant decline in bilateral vestibular function. Based on the examination results, we have provided more comprehensive treatment and lifestyle recommendations to better ensure her safety during activities.
骨化性迷路炎（LO）是迷路炎的终末期。现有的病例报告主要围绕听力损失展开，而忽视了一个关键方面，即LO患者经常会出现平衡问题，而我们的研究填补了这一空白。我们报告了一例罕见的双侧迷路炎病例，该病例继发于脑膜炎，在十多年间耳蜗和前庭症状反复波动，且迷路存在不完全骨化。
一名8个月大的女性患者被诊断为脑膜炎，随后出现发育迟缓及听力问题。4至5岁时，她左耳完全性感音神经性听力损失。13岁时，她开始出现右耳问题，如听力下降和耳闷。计算机断层扫描和钆增强磁共振成像显示内耳有特定变化，前庭功能下降。在治疗过程中，患者最初右耳听力有所改善。然而，其听觉功能随后恶化，最终接受了人工耳蜗植入手术。幸运的是，经过综合治疗方案，患者的平衡功能恢复，头晕症状不再复发。
该患者患有罕见形式的迷路炎，在病程较长的时间里耳蜗和前庭症状波动。尽管在此过程中皮质类固醇治疗有暂时疗效，但最终仍需要进行人工耳蜗植入。治疗期间，我们特别关注了患者的前庭功能，观察到双侧前庭功能显著下降。根据检查结果，我们提供了更全面的治疗和生活方式建议，以更好地确保她活动期间的安全。
