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经腹腹腔镜肾盂成形术治疗婴幼儿肾盂输尿管连接部梗阻的辅助悬吊固定技术:一项回顾性队列研究

An assisted suspension fixation technique in transperitoneal laparoscopic pyeloplasty for infants and young children with ureteropelvic junction obstruction: a retrospective cohort study.

作者信息

Wang Hua, Xia Tian, Xiao Chutian, Li Houhe, He Xionglong, Qiao Yuming, Zhong Meinong, Wang Dejuan, Li Ke

机构信息

Department of Urology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Department of Urology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

出版信息

Transl Androl Urol. 2025 Mar 30;14(3):820-830. doi: 10.21037/tau-2024-722. Epub 2025 Mar 26.

Abstract

BACKGROUND

Anderson-Hynes pyeloplasty is a classic and highly effective technique for treating congenital ureteropelvic junction obstruction (UPJO). Laparoscopic minimally invasive surgery (MIS) has become the preferred approach for infants and young children. However, a small working area and the complexity of reconstruction procedure pose significant challenges. This study aims to evaluate the efficacy and safety of four-point suspension fixation technique in laparoscopic dismembered pyeloplasty (LDP) for infants and young children with UPJO.

METHODS

This retrospective cohort enrolled 37 infants and young children diagnosed with UPJO and underwent transperitoneal LDP between 2014 and 2020. The 37 cases were divided into two Groups based on whether suspension fixation was applied during the transperitoneal LDP. Clinical characteristics and follow-up data of these cohorts were retrospectively collected and analyzed. Continuous variables with a normal distribution were expressed as mean ± standard deviation (SD) and analyzed using independent sample -tests. Non-normally distributed continuous variables were reported as interquartile range (IQR) and analyzed with the Mann-Whitney -test.

RESULTS

In Group A, 21 cases underwent conventional LDP without suspension fixation, while in Group B, 16 cases underwent "suspension fixation" LDP. The operative time (237.9±63.0 186.4±52.3 min, P=0.01), anastomotic suturing completion time (125.2±21.6 75.9±12.1 min, P<0.001), and postoperative hospital stay duration [6.0 (4.0, 7.5) 4.5 (3.0, 6.5) days, P=0.04] were significantly shorter in Group B than in Group A, and the intraoperative blood loss [15.0 (5.0, 21.0) 7.5 (5.0, 10.8) mL, P=0.04] in Group B was significantly lower than that in Group A. There were no significant differences between the two Groups in preoperative and anteroposterior renal pelvic diameter (APD), postoperative days to drainage tube removal, and postoperative days to removal of double J (D-J) sent. In Group A, one case developed anastomotic stenosis during follow-up, which improved after ureteral balloon dilation. In Group B, one case developed recurrent febrile urinary tract infection (UTI) within two months of D-J stent removal and was ultimately cured with antibiotic treatment during follow-up. The success rates were 95.2% (20/21) in Group A and 93.8% (15/16) in Group B. Other cases who were followed up showed no recurrence of stenosis, urine leakage, or recurrent UTI.

CONCLUSIONS

The use of assisted suspension fixation in transperitoneal LDP is safe and efficient for infants and young children, helping to reduce operative time, overcome the small laparoscopic operating area, and address the steep learning curve, making it a valuable approach.

摘要

背景

安德森-海因斯肾盂成形术是治疗先天性肾盂输尿管连接部梗阻(UPJO)的经典且高效的技术。腹腔镜微创手术(MIS)已成为婴幼儿的首选治疗方法。然而,手术操作空间狭小以及重建过程的复杂性带来了巨大挑战。本研究旨在评估四点悬吊固定技术在腹腔镜离断性肾盂成形术(LDP)治疗婴幼儿UPJO中的疗效和安全性。

方法

本回顾性队列研究纳入了2014年至2020年间37例诊断为UPJO并接受经腹LDP的婴幼儿。根据经腹LDP术中是否应用悬吊固定,将这37例病例分为两组。对这些队列的临床特征和随访数据进行回顾性收集和分析。呈正态分布的连续变量以均数±标准差(SD)表示,并采用独立样本t检验进行分析。非正态分布的连续变量以四分位数间距(IQR)报告,并采用曼-惠特尼U检验进行分析。

结果

A组21例接受了未行悬吊固定的传统LDP,而B组16例接受了“悬吊固定”LDP。B组的手术时间(237.9±63.0对186.4±52.3分钟,P = 0.01)、吻合口缝合完成时间(125.2±21.6对75.9±12.1分钟,P < 0.001)和术后住院时间[6.0(4.0,7.5)对4.5(3.0,6.5)天,P = 0.04]均显著短于A组,且B组术中出血量[15.0(5.0,21.0)对7.5(5.0,10.8)毫升,P = 0.04]显著低于A组。两组术前和术后肾盂前后径(APD)、术后引流管拔除天数以及术后双J管(D-J管)拔除天数之间均无显著差异。A组1例在随访期间发生吻合口狭窄,经输尿管球囊扩张后好转。B组1例在拔除D-J支架后两个月内发生复发性发热性尿路感染(UTI),最终在随访期间经抗生素治疗治愈。A组成功率为95.2%(20/21),B组为93.8%(15/16)。其他接受随访的病例未出现狭窄、尿漏或复发性UTI复发。

结论

在经腹LDP中使用辅助悬吊固定对婴幼儿安全有效,有助于缩短手术时间、克服腹腔镜操作空间狭小问题并应对陡峭的学习曲线,是一种有价值的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca6/11986522/8ff4a6b4e5c5/tau-14-03-820-f1.jpg

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