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未得到充分重视的膀胱活动低下

The underappreciated underactive bladder.

作者信息

Razi Basil, Zhuo Kevin, Cole-Clark Dane, Chung Amanda

机构信息

Department of Urology, Royal North Shore Hospital, St Leonards, NSW, Australia.

North Shore Urology Research Group (NSURG), St Leonards, NSW, Australia.

出版信息

Transl Androl Urol. 2025 Mar 30;14(3):841-847. doi: 10.21037/tau-2025-61. Epub 2025 Mar 26.

Abstract

Slow urinary flow is a common lower urinary tract symptom (LUTS) that frequently prompts men to consult their primary care physician. While bladder outlet obstruction (BOO) is well recognised, underactive bladder (UAB) remains underappreciate despite its significant impact on quality of life. This review highlights the pathophysiology, clinical features, and diagnostic challenges and approach to UAB in men. Improving recognition of UAB as a distinct condition separate from other LUTS aetiologies, it can facilitate earlier diagnosis and management. Slow urinary flow is highly prevalent, particularly in an ageing population. UAB is characterised by impaired detrusor muscle activity, leading to slow urinary flow, hesitancy, straining and incomplete bladder emptying. The overlap in symptoms with BOO often leads to misdiagnosis, delaying appropriate intervention. UAB has multiple underlying causes including, neurogenic, myogenic, iatrogenic and idiopathic factors. Diagnosis is further complicated by the limited availability of urodynamic studies, the gold standard for assessing detrusor underactivity. Current management options remain limited with no definitive treatments. Current strategies focus on behavioural modifications, pelvic floor exercises, timed voiding, sacral neuromodulation and intermittent catheterisation. Increased awareness of UAB among primary care physicians and urologists is essential for timely diagnosis and intervention. Recognition of UAB as a distinct clinical entity will lead to a reduction in potential complications and significant improvement in the quality of life of affected men.

摘要

排尿缓慢是一种常见的下尿路症状(LUTS),常促使男性咨询其初级保健医生。虽然膀胱出口梗阻(BOO)已得到充分认识,但膀胱活动低下(UAB)尽管对生活质量有重大影响,却仍未得到充分重视。本文综述了男性UAB的病理生理学、临床特征、诊断挑战及诊断方法。提高对UAB作为一种与其他LUTS病因不同的独特病症的认识,有助于早期诊断和管理。排尿缓慢非常普遍,尤其是在老年人群中。UAB的特征是逼尿肌活动受损,导致排尿缓慢、排尿犹豫、用力排尿及膀胱排空不全。其症状与BOO的重叠常导致误诊,延误适当干预。UAB有多种潜在病因,包括神经源性、肌源性、医源性和特发性因素。尿动力学检查是评估逼尿肌活动低下的金标准,但因可用性有限,使诊断进一步复杂化。目前的治疗选择仍然有限,尚无明确的治疗方法。当前的策略侧重于行为改变、盆底肌锻炼、定时排尿、骶神经调节和间歇性导尿。提高初级保健医生和泌尿科医生对UAB的认识对于及时诊断和干预至关重要。将UAB识别为一种独特的临床实体将减少潜在并发症,并显著改善受影响男性的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e216/11986530/25fcb4fe5f72/tau-14-03-841-f1.jpg

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