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将尿培养作为降低软性膀胱镜检查术后泌尿道感染手段的成本效益微观分析:两个中心的比较研究

Cost benefit micro-analysis of performing urine cultures as a mean to reduce post-flexible cystoscopy urosepsis: a comparative study between two centres.

作者信息

Rahman Adib, Qiu Matthew, Ravichandran Kapilan, Desai Devang

机构信息

Department of Urology, Toowoomba Base Hospital, Queensland Health, Queensland, Australia.

Department of Urology, Redcliffe Hospital, Queensland Health, Queensland, Australia.

出版信息

Transl Androl Urol. 2025 Mar 30;14(3):707-714. doi: 10.21037/tau-24-417. Epub 2025 Mar 26.

DOI:10.21037/tau-24-417
PMID:40226084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11986491/
Abstract

BACKGROUND

In Australia, flexible cystoscopy is a key diagnostic tool in urology, employed to manage various conditions. However, it carries risks like urinary tract infections and urosepsis, which lead to significant healthcare expenses. This study evaluates the cost-effectiveness of pre-procedure urine cultures to prevent post-cystoscopy urosepsis.

METHODS

A retrospective analysis of data from regional Toowoomba Base Hospital and metropolitan Gold Coast University Hospital was conducted to assess the efficacy of urine cultures in reducing urosepsis following flexible cystoscopy. The study reviewed patient records, analysing both the incidence of post-procedure urosepsis and the associated economic impact.

RESULTS

The incidence of post-procedure urosepsis was found to be exceptionally low at 0.03%. Comparative analysis showed no significant reduction in urosepsis rates with the use of pre-procedure urine cultures (P=0.93). The financial analysis highlighted that the regional centre, which conducted urine cultures, incurred costs $ 26.14 per patient greater compared to the metropolitan centre that did not perform these cultures.

CONCLUSIONS

The study indicates that the low incidence of urosepsis does not justify the routine use of pre-operative urine cultures, given the substantial costs involved. These findings support current guidelines that do not recommend routine pre-procedure cultures for cystoscopy due to lack of evidence of benefit.

摘要

背景

在澳大利亚,软性膀胱镜检查是泌尿外科的一项关键诊断工具,用于处理各种病症。然而,它存在诸如尿路感染和尿脓毒症等风险,会导致高额的医疗费用。本研究评估术前尿培养预防膀胱镜检查后尿脓毒症的成本效益。

方法

对图文巴地区基础医院和大都市黄金海岸大学医院的数据进行回顾性分析,以评估尿培养在降低软性膀胱镜检查后尿脓毒症方面的疗效。该研究查阅了患者记录,分析术后尿脓毒症的发生率及相关经济影响。

结果

发现术后尿脓毒症的发生率极低,为0.03%。比较分析表明,使用术前尿培养并未显著降低尿脓毒症发生率(P = 0.93)。财务分析强调,进行尿培养的地区中心,与未进行这些培养的大都市中心相比,每位患者的成本高出26.14美元。

结论

该研究表明,鉴于涉及的成本巨大,尿脓毒症的低发生率并不足以证明术前常规进行尿培养是合理的。这些发现支持了当前的指南,即由于缺乏获益证据,不建议膀胱镜检查术前常规进行培养。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1093/11986491/c3b104866601/tau-14-03-707-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1093/11986491/bebf05ca2a71/tau-14-03-707-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1093/11986491/c3b104866601/tau-14-03-707-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1093/11986491/bebf05ca2a71/tau-14-03-707-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1093/11986491/c3b104866601/tau-14-03-707-f2.jpg

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Can J Urol. 2022 Dec;29(6):11361-11365.
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