Altunay Ilknur Kivanc, Tekin Cemre Akpulat, Aptoula Sena Inal, Aksu Asli, Kurt Birgul Ozkesici
Department of Dermatology, University of Health Sciences Türkiye, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Türkiye.
Department of Dermatology, University of Health Sciences Türkiye, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Türkiye.
Sisli Etfal Hastan Tip Bul. 2025 Mar 18;59(1):28-34. doi: 10.14744/SEMB.2024.40374. eCollection 2025.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder in which patients with HS experience profound deterioration in their overall well-being, psychological state and quality of life. This study aimed to evaluate the psychological impact of HS and examined its associations with relevant factors, including sociodemographic and disease-related characteristics.
A prospective, single-center study was conducted involving 80 patients with HS. The demographic and clinical characteristics of patients were recorded. Depression Anxiety Stress Scale-21 (DASS-21), Dermatology Life Quality Index (DLQI), and General Health Questionnaire-12 (GHQ-12) were used to assess the psychosocial impact of HS.
A significant proportion of patients with HS had severe and extremely severe scores in depression, anxiety and stress, with 48.75%, 52.5%, and 48.75% of patients, respectively. Sixty percent of the patients exhibited high psychological disorders while 53.8% experienced severe impairment in their quality of life (QoL). Sociodemographic and clinical factors were evaluated for associations with the scales used in this study. DASS-21 Anxiety (DASS-21A) was significantly positively correlated with lower education levels and higher body mass index (BMI) (p<0.05). There were no significant correlations between the Hurley stages and the other three scales, except for the DASS-21 Stress (DASS-21S) subscale. Patients with a family history had higher DASS-21A, DASS-21 Depression (DASS-21D), DASS-21S, and GHQ-12 (both Likert and traditional scoring) scores compared to those without a family history (p<0.05). Additionally, a positive family history significantly predicted higher scores on DASS-21A, DASS-21D, and DASS-21S (p=0.002; p=0.019; p=0.022, respectively).
Our findings confirm that a significant proportion of patients with HS had high or extremely high levels on all three scales assessing the psychological burden of HS. Patients were negatively affected psychologically at each Hurley stage. Family history proved to be a strong predictive factor contributing to impaired psychosocial status among individuals with HS. Thus, dermatologists should provide extra care, especially for those with family members affected by this condition.
化脓性汗腺炎（HS）是一种慢性炎症性皮肤病，HS患者的整体幸福感、心理状态和生活质量会严重恶化。本研究旨在评估HS对心理的影响，并探讨其与包括社会人口统计学和疾病相关特征在内的相关因素之间的关联。
进行了一项前瞻性单中心研究，纳入80例HS患者。记录患者的人口统计学和临床特征。使用抑郁焦虑压力量表-21（DASS-21）、皮肤病生活质量指数（DLQI）和一般健康问卷-12（GHQ-12）评估HS对心理社会的影响。
相当一部分HS患者在抑郁、焦虑和压力方面的得分达到重度和极重度，分别有48.75%、52.5%和48.75%的患者。60%的患者存在高度心理障碍，53.8%的患者生活质量（QoL）严重受损。评估了社会人口统计学和临床因素与本研究中使用的量表之间的关联。DASS-21焦虑量表（DASS-21A）与较低的教育水平和较高的体重指数（BMI）显著正相关（p<0.05）。除DASS-21压力量表（DASS-21S）子量表外，Hurley分期与其他三个量表之间无显著相关性。有家族史的患者与无家族史的患者相比，DASS-21A、DASS-21抑郁量表（DASS-21D）、DASS-21S和GHQ-12（李克特量表和传统评分）得分更高（p<0.05）。此外，家族史阳性显著预测DASS-21A、DASS-21D和DASS-21S得分更高（分别为p=0.002；p=0.019；p=0.022）。
我们的研究结果证实，相当一部分HS患者在评估HS心理负担的所有三个量表上得分都很高或极高。在Hurley分期的每个阶段，患者的心理都受到负面影响。家族史被证明是导致HS患者心理社会状态受损的一个强有力的预测因素。因此，皮肤科医生应给予额外关注，尤其是对那些有家庭成员受此病影响的患者。
