Liu Hui, Wang Linqi, Tan Xiaoying, Zhang Jian, Xia Xue
Shanghai Punan Hospital of Pudong New District, Shanghai, China.
School of Psychology, Shanghai University of Sport, Shanghai, China.
Depress Anxiety. 2024 Sep 24;2024:5532347. doi: 10.1155/2024/5532347. eCollection 2024.
Abnormal emotional perception may contribute to emotional dysfunction in individuals with anxiety. This study explored the progression of impaired emotional perception with the deepening of anxiety in individuals with nonclinical trait anxiety, by measuring the motor cortical excitability associated with emotional perception. In total, 87 participants were assigned to a high trait anxiety ( = 27), moderate trait anxiety ( = 30), or low trait anxiety ( = 30) group. Transcranial magnetic stimulation was applied to the right primary motor cortex at 150 ms or 300 ms after the onset of positive, negative, or neutral images, while participants performed an emotion recognition task, and motor-evoked potentials (MEPs) were collected. For participants with low trait anxiety, MEP amplitudes were significantly higher for both negative and positive stimuli than for neutral stimuli. Participants with moderate trait anxiety showed significantly higher MEP amplitudes only for negative stimuli. Participants with high trait anxiety showed no significant difference in MEP amplitudes for positive, negative, and neutral stimuli. Trait anxiety score was negatively correlated with MEP amplitude: For higher trait anxiety scores, MEP amplitudes were correlated with lower emotional perception of positive and negative stimuli. Findings suggest that anxiety impairs emotional perception-related motor cortical excitability, starting with decreased motor cortical excitability responses to positive information and progressing to negative information as anxiety levels increase.
异常的情绪感知可能导致焦虑个体出现情绪功能障碍。本研究通过测量与情绪感知相关的运动皮层兴奋性，探讨了非临床特质焦虑个体中随着焦虑程度加深情绪感知受损的进展情况。总共87名参与者被分为高特质焦虑组（n = 27）、中度特质焦虑组（n = 30）或低特质焦虑组（n = 30）。在呈现正性、负性或中性图像150毫秒或300毫秒后，对右侧初级运动皮层施加经颅磁刺激，同时参与者执行情绪识别任务，并收集运动诱发电位（MEP）。对于低特质焦虑的参与者，负性和正性刺激的MEP波幅均显著高于中性刺激。中度特质焦虑的参与者仅在负性刺激时MEP波幅显著更高。高特质焦虑的参与者在正性、负性和中性刺激的MEP波幅上没有显著差异。特质焦虑得分与MEP波幅呈负相关：特质焦虑得分越高，MEP波幅与对正性和负性刺激的情绪感知越低相关。研究结果表明，焦虑会损害与情绪感知相关的运动皮层兴奋性，首先是对正性信息的运动皮层兴奋性反应降低，随着焦虑水平的增加，进而发展到对负性信息的反应。
