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[McCune-Albright综合征中的假性性早熟]

[Pseudo precocious puberty in the McCune-Albright syndrome].

作者信息

Bost M, Andrini P, Jean D

出版信息

Pediatrie. 1985 Jan-Feb;40(1):55-60.

PMID:4022718
Abstract

McCune Albright Syndrome is characterized by the triad of polyostostic fibrous dysplasia of bones, skin pigmentation (café au lait-spots) and sexual precocity. The authors report a case of a 7 years girl with this syndrome in whom the sexual precocity is due to an autonomous hyperfunctioning of luteinized follicular cysts of ovary. The pathogenic mechanisms of this autonomy are debate.

摘要

McCune-Albright综合征的特征为骨的多骨型纤维性发育不良、皮肤色素沉着(咖啡牛奶斑)和性早熟三联征。作者报告了1例患有该综合征的7岁女孩,其性早熟是由卵巢黄素化滤泡囊肿自主功能亢进所致。这种自主性的致病机制存在争议。

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