放射性碘（I131）治疗甲状腺癌导致的性腺损伤。
Gonadal damage due to radioactive iodine (I131) treatment for thyroid carcinoma.
作者信息
Ahmed S R, Shalet S M
出版信息
Postgrad Med J. 1985 Apr;61(714):361-2. doi: 10.1136/pgmj.61.714.361.
Abstract
Papillary carcinoma of the thyroid is the most common type of thyroid cancer and is associated with a good prognosis. Complications of treatment with surgery and radioiodine are uncommon. We report the case of a 13 year old boy who developed testicular damage following treatment with radioactive iodine 350 mCi for a papillary carcinoma of the thyroid. Four years after radioiodine treatment there has been no suggestion of recovery of spermatogenesis. Detailed follow-up studies of similarly treated young patients are required to define the incidence of this complication and to determine its reversibility.
摘要
甲状腺乳头状癌是最常见的甲状腺癌类型，预后良好。手术和放射性碘治疗的并发症并不常见。我们报告了一名13岁男孩的病例，他在接受350毫居里放射性碘治疗甲状腺乳头状癌后出现了睾丸损伤。放射性碘治疗四年后，仍没有精子发生恢复的迹象。需要对接受类似治疗的年轻患者进行详细的随访研究，以确定这种并发症的发生率并确定其可逆性。
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