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Caution when analyzing zero events in both arms: reanalysis of anaphylaxis risk for gelatin solutions.

作者信息

Hung Hsiang-Yi, Lai Pei-Chun, Huang Yen-Ta, Lai Chao-Han

机构信息

Department of Neurosurgery, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

Institute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.

出版信息

Crit Care. 2025 Apr 14;29(1):151. doi: 10.1186/s13054-025-05388-6.

DOI:10.1186/s13054-025-05388-6
PMID:40229871
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11998389/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5160/11998389/856aea2f9a8b/13054_2025_5388_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5160/11998389/856aea2f9a8b/13054_2025_5388_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5160/11998389/856aea2f9a8b/13054_2025_5388_Fig1_HTML.jpg

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本文引用的文献

1
Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.拯救脓毒症运动：2021年脓毒症和脓毒性休克国际管理指南
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
2
A randomized, controlled, double-blind crossover study on the effects of isoeffective and isovolumetric intravenous crystalloid and gelatin on blood volume, and renal and cardiac hemodynamics.一项关于等效应和等容量静脉输注晶体液与明胶对血容量、肾和心脏血流动力学影响的随机、对照、双盲交叉研究。
Clin Nutr. 2020 Jul;39(7):2070-2079. doi: 10.1016/j.clnu.2019.09.011. Epub 2019 Oct 16.
3
Effects of Intraoperative Gelatin on Blood Viscosity and Oxygenation Balance.
J Perianesth Nurs. 2019 Dec;34(6):1274-1281. doi: 10.1016/j.jopan.2019.05.136. Epub 2019 Sep 3.
4
How safe is gelatin? A systematic review and meta-analysis of gelatin-containing plasma expanders vs crystalloids and albumin.明胶的安全性如何？含明胶的血浆代用品与晶体液和白蛋白的系统评价与荟萃分析。
J Crit Care. 2016 Oct;35:75-83. doi: 10.1016/j.jcrc.2016.04.011. Epub 2016 Apr 23.
5
Inclusion of zero total event trials in meta-analyses maintains analytic consistency and incorporates all available data.在荟萃分析中纳入零总事件试验可保持分析的一致性并纳入所有可用数据。
BMC Med Res Methodol. 2007 Jan 23;7:5. doi: 10.1186/1471-2288-7-5.