Desale Prasad, Dhande Rajasbala, Parihar Pratapsingh, Mishra Gaurav, Gaur Shubhi
Department of Radio Diagnosis, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.
Radiol Case Rep. 2025 Mar 29;20(6):3037-3040. doi: 10.1016/j.radcr.2025.02.105. eCollection 2025 Jun.
Atretic cephaloceles, grey matter heterotopia, and septo-optic dysplasia are uncommon congenital cerebral malformations commonly diagnosed in children. The case is a rare one in which atretic parietal cephalocele, grey matter heterotopia, and septo-optic dysplasia are seen concurrently and diagnosed in a 60-year-old man with a history of focal onset seizures. In contrast to their congenital origin, the patient never experienced antecedent neurodevelopmental delay or significant endocrine disturbances. The case requires the consideration of the role of MRI in identifying unsuspected congenital cerebral malformations in adult patients with seizures and performing a complete neurological and ophthalmological examination in these patients.
闭锁性脑膨出、灰质异位症和视隔发育不良是儿童中常见的先天性脑畸形。该病例较为罕见,一名有局灶性发作病史的60岁男性同时出现闭锁性顶叶脑膨出、灰质异位症和视隔发育不良并被诊断出来。与它们的先天性起源不同,该患者从未经历过先前的神经发育延迟或明显的内分泌紊乱。该病例需要考虑MRI在识别成年癫痫患者中未被怀疑的先天性脑畸形以及对这些患者进行全面的神经和眼科检查方面的作用。