Liang Na, Chen Changxian, Yuan Dan, Xu Qiang, Zhan Yali, Zhao Yi, Wu Di, Yang Cheng, Li Chunming
Department of Pathology, School of Basic Medicine, Zunyi Medical University, Zunyi, China.
Department of Pathology, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Front Oncol. 2025 Mar 31;15:1551157. doi: 10.3389/fonc.2025.1551157. eCollection 2025.
Histiocytic sarcoma (HS) is a rare malignant tumor that primarily affects the lymph nodes, intestines, skin, and soft tissues. Primary central nervous system histiocytic sarcoma (PCNSHS) is even rarer. We present the case of a 50-year-old Asian male with PCNSHS who was hospitalized after experiencing intermittent headaches and slurred speech for a week. During surgery, both tumor cells and purulent material were observed, and the diagnosis of PCNSHS was ultimately confirmed by immunohistochemistry. Furthermore, we conducted a literature review from 1952 to the present, screening and analyzing 49 related cases across 41 publications.
组织细胞肉瘤（HS）是一种罕见的恶性肿瘤，主要累及淋巴结、肠道、皮肤和软组织。原发性中枢神经系统组织细胞肉瘤（PCNSHS）更为罕见。我们报告一例50岁亚洲男性原发性中枢神经系统组织细胞肉瘤患者，该患者在经历了一周的间歇性头痛和言语不清后住院。手术中观察到肿瘤细胞和脓性物质，最终通过免疫组织化学确诊为原发性中枢神经系统组织细胞肉瘤。此外，我们对1952年至今的文献进行了综述，筛选并分析了41篇出版物中的49例相关病例。
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