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[慢性照射大鼠外周血细胞的定量和定性变化]

[Quantitative and qualitative changes in the peripheral blood cells of rats in chronic irradiation of the animals].

作者信息

Ivanov V V, Strel'tsova V N

出版信息

Radiobiologiia. 1985 May-Jun;25(3):372-5.

PMID:4023189
Abstract

A study was made of qualitative and quantitative changes in peripheral blood lymphocytes of rats subjected to continuous totalbody gamma-irradiation at dose--rates from 0.002 to 0.35 Gy/day and cumulative doses from 0.7 to 20.0 Gy. After termination of irradiation (on the 400th-500th day), the number of lymphocytes changed in an undulatory manner, i. e., increased at a dose--rate of 0.008 Gy/day, and decreased down to minimum control values at a dose--rate of 0.35 Gy/day, and the fraction of young macrocellular forms increased. The effect increased with increase in dose--rate and cumulative dose.

摘要

对连续全身γ射线照射的大鼠外周血淋巴细胞的质和量的变化进行了研究,照射剂量率为0.002至0.35 Gy/天,累积剂量为0.7至20.0 Gy。照射结束后(第400 - 500天),淋巴细胞数量呈波动变化,即在剂量率为0.008 Gy/天时增加,而在剂量率为0.35 Gy/天时降至最低对照值,并且年轻大细胞形态的比例增加。该效应随剂量率和累积剂量的增加而增强。

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