泄密的心：原位心脏移植受者中的供体来源侵袭性真菌感染

Krishnan Jay, Carugati Manuela, Miller Rachel A, Wolfe Cameron R, Perfect John R, Messina Julia A

Duke University, Division of Infectious Diseases, Department of Medicine, Duke University Medical Center, Durham, NC, USA.

Med Mycol Case Rep. 2025 Mar 31;48:100702. doi: 10.1016/j.mmcr.2025.100702. eCollection 2025 Jun.

Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections - one complex infection and one infection - that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.

实体器官移植受者中供体来源的侵袭性真菌感染很少见，但有时是具有显著发病率和死亡率的灾难性事件。在此，我们描述了在一家四级医疗中心心脏移植受者中发生的两例供体来源的真菌感染——一例复杂感染和一例单一感染。两名受者均从感染中存活下来，尽管经过积极的手术干预和抗真菌治疗，仍有严重的发病率。