Mamtani Sahil, Aljanabi Nawar Muneer, Gupta Rauniyar Robins P, Acharya Ashu, Malik Bilal Haider
Infectious Diseases Research, Veterans Affairs Medical Center, Lebanon, USA.
Internal Medicine, California Institute of Behavioral Neurosciences and Psychology, Fairfield, USA.
Cureus. 2020 Jan 18;12(1):e6695. doi: 10.7759/cureus.6695.
Infective endocarditis is a significant healthcare burden due to the associated high mortality and complications. Endocarditis caused by both and non- (NCAC) species has been associated with a substantial rise in in-hospital morbidity and mortality. We used the Pubmed database to identify 47 out of 101 articles that had met our inclusion and exclusion criteria. We had put in place a broad inclusion criterion with no age or gender restrictions. These 47 articles included abstracts, 11 review articles, 13 case reports, 10 research articles, 1 clinical trial report, 1 meta-analysis, and other research articles. And they comprehensively cover the pathogenesis, risk factors, and management of infections caused by and NCAC species in the past 26 years. The articles we scanned provided us with information on different associations in correlation to multiple types of species. Here, we discuss the association between and endocarditis, a major cause of morbidity and mortality in both and NCAC. We also present our understanding regarding this interesting association and attempt to address some of the recurring questions.
感染性心内膜炎由于其相关的高死亡率和并发症，是一个重大的医疗负担。由[具体菌种]和非[具体菌种]（NCAC）引起的心内膜炎与住院发病率和死亡率的大幅上升有关。我们使用PubMed数据库从101篇文章中筛选出47篇符合我们纳入和排除标准的文章。我们制定了广泛的纳入标准，没有年龄或性别限制。这47篇文章包括摘要、11篇综述文章、13篇病例报告、10篇研究文章、1篇临床试验报告、1篇荟萃分析和其他研究文章。它们全面涵盖了过去26年中由[具体菌种]和NCAC引起的感染的发病机制、危险因素和管理。我们浏览的文章为我们提供了与多种[具体菌种]类型相关的不同关联信息。在此，我们讨论[具体菌种]与心内膜炎之间的关联，心内膜炎是[具体菌种]和NCAC发病和死亡的主要原因。我们还阐述了我们对这种有趣关联的理解，并试图解决一些反复出现的问题。
