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一种新型的多动功能障碍综合征合并症:一个独特病例。

A New Form of Combined Hyperactive Dysfunction Syndrome: A Unique Case.

作者信息

Messina Christian

机构信息

Department "G. F. Ingrassia" Section of Neuroscience, University of Catania, Catania, ITA.

出版信息

Cureus. 2025 Mar 15;17(3):e80639. doi: 10.7759/cureus.80639. eCollection 2025 Mar.

DOI:10.7759/cureus.80639
PMID:40236341
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11997537/
Abstract

Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage. There are different types of pain. Neuropathic pain is caused by a lesion or pathological condition of the somatosensory nervous system. One of the most well-known neuropathic pains is trigeminal neuralgia (TN). However, occipital neuralgia (ON) and glossopharyngeal neuralgia (GPN) exist. These three rare pathologies occur in a very small part of the global population. Combined hyperactive dysfunction syndrome is a rare disorder characterized by overactivity in different cranial nerves, TN, hemifacial spasm, and GPN. In this paper, we present a very rare case of a young woman affected by an association of overactivity in the trigeminal, occipital, and glossopharyngeal nerves, leading to TN, ON, and GPN simultaneously.

摘要

疼痛是一种与实际的或潜在的组织损伤相关的不愉快的感觉和情感体验。疼痛有不同类型。神经性疼痛由躯体感觉神经系统的损伤或病理状况引起。最著名的神经性疼痛之一是三叉神经痛(TN)。然而,枕神经痛(ON)和舌咽神经痛(GPN)也存在。这三种罕见病症在全球人口中发生的比例非常小。联合性功能亢进综合征是一种罕见的疾病,其特征是不同颅神经功能亢进、三叉神经痛、面肌痉挛和舌咽神经痛。在本文中,我们报告了一例非常罕见的年轻女性病例,她同时患有三叉神经、枕神经和舌咽神经功能亢进,导致同时出现三叉神经痛、枕神经痛和舌咽神经痛。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/11997537/d85b5f978ff6/cureus-0017-00000080639-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/11997537/d85b5f978ff6/cureus-0017-00000080639-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6504/11997537/d85b5f978ff6/cureus-0017-00000080639-i01.jpg

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本文引用的文献

1
Glossopharyngeal neuralgia as initial symptom in combined hyperactive dysfunction syndrome: case report.以舌咽神经痛为首发症状的多动功能亢进综合征:病例报告
Br J Neurosurg. 2023 Jun;37(3):309-312. doi: 10.1080/02688697.2020.1817317. Epub 2020 Sep 11.
2
The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises.修订后的国际疼痛研究协会疼痛定义:概念、挑战和妥协。
Pain. 2020 Sep 1;161(9):1976-1982. doi: 10.1097/j.pain.0000000000001939.
3
Trigeminal Neuralgia: Basic and Clinical Aspects.
三叉神经痛:基础与临床方面。
Curr Neuropharmacol. 2020;18(2):109-119. doi: 10.2174/1570159X17666191010094350.
4
A Unique Case of Microvascular Triple Decompression for Combined Simultaneous Trigeminal Neuralgia, Hemifacial Spasm, and Glossopharyngeal Neuralgia Because of the Dolichoectatic Vertebrobasilar System.一例因椎动脉延长扩张症导致三叉神经痛、半面痉挛和舌咽神经痛同时发作而行微血管三联减压术的独特病例。
Oper Neurosurg (Hagerstown). 2020 Jun 1;18(6):692-697. doi: 10.1093/ons/opz205.
5
Combined Hyperactive Dysfunction Syndrome of the Cranial Nerves: Analysis of 37 Cases and Literature Review.颅神经联合亢进功能障碍综合征:37 例分析及文献复习。
World Neurosurg. 2019 Sep;129:e650-e656. doi: 10.1016/j.wneu.2019.05.237. Epub 2019 May 31.
6
The Neuralgias.神经痛。
Curr Neurol Neurosci Rep. 2018 Aug 16;18(10):69. doi: 10.1007/s11910-018-0880-0.
7
Combined Hyperactive Dysfunction Syndrome of the Cranial Nerves: A Retrospective Systematic Study of Clinical Characteristics in 44 Patients.颅神经联合多动功能障碍综合征:44例患者临床特征的回顾性系统研究
World Neurosurg. 2017 Aug;104:390-397. doi: 10.1016/j.wneu.2017.05.020. Epub 2017 May 13.
8
Neuralgias of the Head: Occipital Neuralgia.头部神经痛:枕神经痛
J Korean Med Sci. 2016 Apr;31(4):479-88. doi: 10.3346/jkms.2016.31.4.479. Epub 2016 Mar 9.
9
Microvascular decompression in patients with coexistent trigeminal neuralgia, hemifacial spasm and glossopharyngeal neuralgia.伴有三叉神经痛、面肌痉挛和舌咽神经痛的患者的微血管减压术。
Acta Neurochir (Wien). 2014 Jun;156(6):1167-71. doi: 10.1007/s00701-014-2034-8. Epub 2014 Mar 7.
10
Combined hyperactive dysfunction syndrome of the cranial nerves.合并性脑神经功能亢进综合征
J Korean Neurosurg Soc. 2009 Oct;46(4):351-4. doi: 10.3340/jkns.2009.46.4.351. Epub 2009 Oct 31.