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一名脊柱强直患者腰骶部夏科氏脊柱关节病病例

A Case of Charcot Spine Arthropathy at the Lumbosacral Level in a Patient With Ankylosis of the Spine.

作者信息

Oda Yoshiaki, Uotani Koji, Tetsunaga Tomoko, Shinohara Kensuke, Ozaki Toshifumi

机构信息

Department of Orthopedic Surgery, Okayama University Hospital, Okayama, JPN.

Department of Musculoskeletal Traumatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, JPN.

出版信息

Cureus. 2025 Mar 16;17(3):e80656. doi: 10.7759/cureus.80656. eCollection 2025 Mar.

DOI:10.7759/cureus.80656
PMID:40236358
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11998860/
Abstract

Charcot spinal arthropathy, a rare refractory progressive disease, is characterized by symptoms such as pain, deformity, and neurological impairment, which can significantly reduce functional ability, quality of life, and life expectancy. We report a case of Charcot spine at the L5/S1 level with long segment ankylosis to the L5 vertebra. We first performed thorough debridement via a posterior approach. We used antibiotic-containing cement as a spacer to fill the dead space, facilitating the second surgery approach. In the second surgery, transdiscal screws, which have a low profile and strong force, were used as anchors, and bulk bone harvested from both iliac bones was grafted to the intervertebral space. The lumbosacral alignment was kyphotic, and the patient could sit and move independently. Disimpaction was impossible, and a stoma had to be created.

摘要

夏科氏脊柱关节病是一种罕见的难治性进行性疾病,其特征为疼痛、畸形和神经功能障碍等症状,这些症状会显著降低功能能力、生活质量和预期寿命。我们报告一例L5/S1水平的夏科氏脊柱病病例,其长节段融合至L5椎体。我们首先通过后路进行了彻底清创。我们使用含抗生素的骨水泥作为间隔物填充死腔,为二次手术入路提供便利。在二次手术中,使用外形低矮且力量强大的经椎间盘螺钉作为锚定物,并将取自双侧髂骨的大块骨移植到椎间隙。腰骶部呈后凸畸形,患者能够独立坐立和活动。无法进行减压,必须造瘘。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/b61b5fe81d86/cureus-0017-00000080656-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/46c62f1ede9f/cureus-0017-00000080656-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/ab0618e2daea/cureus-0017-00000080656-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/6bce315bef5a/cureus-0017-00000080656-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/0b7a5f41ef75/cureus-0017-00000080656-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/b607487133d9/cureus-0017-00000080656-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/b61b5fe81d86/cureus-0017-00000080656-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/46c62f1ede9f/cureus-0017-00000080656-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/ab0618e2daea/cureus-0017-00000080656-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/6bce315bef5a/cureus-0017-00000080656-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/0b7a5f41ef75/cureus-0017-00000080656-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/b607487133d9/cureus-0017-00000080656-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b7d/11998860/b61b5fe81d86/cureus-0017-00000080656-i06.jpg

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本文引用的文献

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A comprehensive review of the treatment and management of Charcot spine.夏科氏脊柱病治疗与管理的全面综述。
Ther Adv Musculoskelet Dis. 2020 Dec 17;12:1759720X20979497. doi: 10.1177/1759720X20979497. eCollection 2020.
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Charcot Spine following chronic spinal cord injury: an analysis of 201 published cases.慢性脊髓损伤后夏科氏脊柱:201例已发表病例分析
Spinal Cord. 2019 Feb;57(2):85-90. doi: 10.1038/s41393-018-0216-6. Epub 2018 Nov 9.
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Charcot spinal arthropathy.夏科氏脊柱关节病
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Transdiscal L5-S1 screws for the fixation of isthmic spondylolisthesis: a biomechanical evaluation.用于峡部裂型腰椎滑脱症固定的经椎间盘L5-S1螺钉:生物力学评估
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