Mittal Mehul M, Acevedo Katalina V, Lee Tiffany M, Singh Aaron, Hosseinzadeh Pooya
Department of Orthopaedics, University of Texas Southwestern Medical Center, Dallas.
Department of Orthopaedics, Baylor College of Medicine, Houston.
J Pediatr Orthop. 2025 Sep 1;45(8):e706-e710. doi: 10.1097/BPO.0000000000002987. Epub 2025 Apr 16.
Hip arthroscopy is a commonly performed procedure in adolescents with hip pathology. However, there is limited data on venous thromboembolism (VTE) events in this population, resulting in minimal guidance on appropriate VTE prophylaxis, with the bulk of current guidance extrapolated from the adult population. Therefore, this study aims to assess overall rates of VTE in the adolescent population as well as compare these rates to a matched cohort of adult patients undergoing hip arthroscopy.
This retrospective cohort study drew data from the TriNetX platform between January 1, 2003 and March 1, 2024. Adolescent patients, ages 13 to 18, were matched to adult patients (19 and older) undergoing hip arthroscopy, accounting for sex, tobacco use, oral contraceptive use, diabetes mellitus, and overweight/obesity. Outcomes of interest were deep vein thrombosis (DVT) or pulmonary embolism (PE) within 90 days after the procedure. Overall rates were calculated and compared between cohorts. Statistical significance was set at P <0.01.
A total of 3655 patients were successfully matched with a mean age of 16 in the adolescent cohort and 35 in the adult cohort. The overall rates of DVT were similar between cohorts, at 1% for adolescent patients and 0.9% for adults (RR: 0.892; 95% CI: 0.559-1.423; P =0.63). All VTE events (combined DVT and PE) were also similar at 1.1% for adolescent patients and 1.0% in adults (RR: 0.925; 95% CI: 0.593-1.443; P =0.73).
This study found no significant difference in VTE between adolescent and adult patients undergoing hip arthroscopy. The overall rate of VTE was relatively high in adolescent patients, at 1.1%, suggesting additional attention to VTE and potential chemoprophylaxis may be warranted in select patients.
Level III-case-control study or retrospective cohort study.
髋关节镜检查是治疗青少年髋关节疾病的常用手术。然而,关于该人群静脉血栓栓塞(VTE)事件的数据有限,导致在适当的VTE预防方面几乎没有指导意见,目前的大部分指导意见是从成人人群推断而来。因此,本研究旨在评估青少年人群中VTE的总体发生率,并将这些发生率与接受髋关节镜检查的匹配成年患者队列进行比较。
这项回顾性队列研究从TriNetX平台提取了2003年1月1日至2024年3月1日的数据。年龄在13至18岁的青少年患者与接受髋关节镜检查的成年患者(19岁及以上)进行匹配,考虑了性别、吸烟情况、口服避孕药使用情况、糖尿病以及超重/肥胖因素。感兴趣的结局是术后90天内发生的深静脉血栓形成(DVT)或肺栓塞(PE)。计算并比较了队列之间的总体发生率。设定统计学显著性为P<0.01。
共有3655例患者成功匹配,青少年队列的平均年龄为16岁,成年队列的平均年龄为35岁。队列之间DVT的总体发生率相似,青少年患者为1%,成年人为0.9%(相对危险度:0.892;95%置信区间:0.559 - 1.423;P = 0.63)。所有VTE事件(合并DVT和PE)在青少年患者中也相似,为1.1%,在成年人中为1.0%(相对危险度:0.925;95%置信区间:0.593 - 1.443;P = 0.73)。
本研究发现接受髋关节镜检查的青少年和成年患者在VTE方面无显著差异。青少年患者的VTE总体发生率相对较高,为1.1%,这表明在特定患者中可能需要额外关注VTE并考虑潜在的化学预防措施。
III级——病例对照研究或回顾性队列研究。