Belete Shiret, Adugna Hunde, Yirsa Tsedalu
School of Veterinary Medicine, Woldia University, Woldia, Ethiopia.
PLoS One. 2025 Apr 16;20(4):e0320867. doi: 10.1371/journal.pone.0320867. eCollection 2025.
An experimental investigation was conducted from December 2023 to June 2024 at the beef farm of Haramaya University. The bulls were divided into two groups: one group received ivermectin treatment, while the other acted as a control. The SUMIVER brand of ivermectin was administered subcutaneously at 1 ml per 50 kg of body weight. Dung samples from both groups were collected and prepared for analysis at five-day intervals during the eighth sampling period. The results were measured, documented, and analyzed both qualitatively and quantitatively. All data were entered and analyzed using an independent t-test with the STATA-14 software. In the qualitative assessment, no dipteran larvae or pupae were detected in the dung samples, except during the eighth round. However, various species of invertebrates were attracted to the freshly managed dung, resulting in a higher visitation rate in the control group compared to the experimental group. In the initial weeks of the study, the presence of ivermectin residues affected the dung beetle population. Conversely, the treated dung showed a significant infestation of termites. After several weeks, both groups of dung pats were invaded by ants, with the control group experiencing infestation first. These findings suggest that ivermectin residues released into the environment through cattle dung can influence negatively plant germination, dung fauna, and soil fertility. Therefore, it is crucial for veterinarians to be knowledgeable about the environmental side effects of ivermectin and to offer guidance to livestock owners.
2023年12月至2024年6月，在哈拉马亚大学的养牛场进行了一项实验研究。公牛被分为两组：一组接受伊维菌素治疗，另一组作为对照组。使用SUMIVER品牌的伊维菌素，按每50公斤体重皮下注射1毫升。在第八个采样期，每隔五天收集两组的粪便样本并准备进行分析。对结果进行了测量、记录，并进行了定性和定量分析。所有数据都使用STATA - 14软件通过独立t检验输入和分析。在定性评估中，除了第八轮外，粪便样本中未检测到双翅目幼虫或蛹。然而，各种无脊椎动物被新鲜处理的粪便吸引，导致对照组的访问率高于实验组。在研究的最初几周，伊维菌素残留的存在影响了蜣螂种群。相反，经处理的粪便显示出白蚁的大量侵扰。几周后，两组粪堆都被蚂蚁入侵，对照组首先受到侵扰。这些发现表明，通过牛粪释放到环境中的伊维菌素残留会对植物发芽、粪便动物群和土壤肥力产生负面影响。因此，兽医了解伊维菌素的环境副作用并为牲畜所有者提供指导至关重要。
