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腹壁巨大硬纤维瘤:一例报告

Giant desmoid tumor of the abdominal wall: a case report.

作者信息

Tormane Mohamed Amine, Laamiri Ghazi, Jbir Ichraf, Ltifi Nada, Bouassida Mahdi, Touinsi Hassen

机构信息

Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia; University Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

Department of General Surgery, Hospital Mohamed Taher Maamouri, Nabeul, Tunisia; University Tunis El Manar, Faculty of Medicine of Tunis, Tunisia.

出版信息

Int J Surg Case Rep. 2025 May;130:111304. doi: 10.1016/j.ijscr.2025.111304. Epub 2025 Apr 15.

DOI:10.1016/j.ijscr.2025.111304
PMID:40239369
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12019195/
Abstract

INTRODUCTION AND IMPORTANCE

Desmoid tumors are a rare type of benign fibromatosis. Patients often present with a painless abdominal mass. Here, we report a case of a giant desmoid tumor of the abdominal wall that was successfully treated with wide local excision.

CASE PRESENTATION

We present the case of a 48-year-old female who developed an abdominal mass over the past year. Imaging revealed a well-circumscribed mass on the left side of the abdomen, which was treated with wide local excision. Immunohistochemical analysis of the specimen confirmed the diagnosis of a desmoid tumor. The patient had an uneventful postoperative recovery and remained in remission during an 18-month follow-up period.

DISCUSSION

Desmoid tumors are very rare benign lesions that typically affect young women. Abdominal wall localization is more common in individuals with Gardner syndrome. Surgery remains the primary treatment, with the approach depending on the size and location of the lesion. Radiotherapy is considered an alternative for tumors that are unresectable or incompletely excised. The definitive diagnosis requires immunohistochemical analysis of the specimen.

CONCLUSION

Desmoid tumors are benign fibromatoses that can occur in the abdominal wall. Symptoms are typically non-specific. Surgery is the main treatment, always aiming for radical resection with free margins. Histological analysis of the surgical specimen is crucial for confirming the diagnosis.

摘要

引言与重要性

硬纤维瘤是一种罕见的良性纤维瘤病。患者常表现为无痛性腹部肿块。在此,我们报告一例腹壁巨大硬纤维瘤,经广泛局部切除成功治疗。

病例介绍

我们呈现一例48岁女性病例,该患者在过去一年中出现腹部肿块。影像学检查显示腹部左侧有一个边界清晰的肿块,经广泛局部切除进行治疗。对标本进行免疫组织化学分析确诊为硬纤维瘤。患者术后恢复顺利,在18个月的随访期内保持缓解状态。

讨论

硬纤维瘤是非常罕见的良性病变,通常影响年轻女性。腹壁定位在患有加德纳综合征的个体中更为常见。手术仍然是主要治疗方法,治疗方式取决于病变的大小和位置。对于不可切除或切除不完全的肿瘤,放疗被认为是一种替代方法。明确诊断需要对标本进行免疫组织化学分析。

结论

硬纤维瘤是可发生于腹壁的良性纤维瘤病。症状通常不具有特异性。手术是主要治疗方法,始终旨在进行切缘阴性的根治性切除。手术标本的组织学分析对于确诊至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/0340cfd9bed8/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/c5ea854843cd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/20fad0099fd9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/78eda3179baa/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/0340cfd9bed8/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/c5ea854843cd/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/20fad0099fd9/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/78eda3179baa/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a21c/12019195/0340cfd9bed8/gr4.jpg

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The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
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Surgical Management of a Giant Desmoid Fibromatosis of Abdominal Wall With Vessels Invasion in a Young Man: A Case Report and Review of the Literature.
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Front Surg. 2022 Apr 11;9:851164. doi: 10.3389/fsurg.2022.851164. eCollection 2022.
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Clinical outcomes of medical treatments for progressive desmoid tumors following active surveillance: a systematic review.主动监测后进行医学治疗的侵袭性硬纤维瘤的临床结果:一项系统综述
Musculoskelet Surg. 2023 Mar;107(1):7-18. doi: 10.1007/s12306-022-00738-x. Epub 2022 Feb 12.
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