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双通道髓芯减压联合髓腔冲洗治疗非创伤性股骨头坏死的临床研究

[Clinical study of double-channel core decompression combined with medullary cavity irrigation for non-traumatic osteonecrosis of femoral head].

作者信息

Ma Jinhui, Li Hongxu, Liu Haoyang, Wang Bailiang, Wang Weiguo, Gao Fuqiang, Sun Wei, Cheng Liming

机构信息

Department of Bone and Joint Surgery, China-Japan Friendship Hospital, Beijing, 100029, P. R. China.

Peking University China-Japan Friendship School of Clinical Medicine, Beijing, 100029, P. R. China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 Apr 15;39(4):399-405. doi: 10.7507/1002-1892.202501039.

Abstract

OBJECTIVE

To compare the effects of double-channel core decompression (CD) combined with medullary cavity irrigation with those of simple CD on progression of collapse and clinical outcomes in non-traumatic osteonecrosis of the femoral head (ONFH).

METHODS

A retrospective analysis was conducted on the clinical data of 19 patients (30 hips) with non-traumatic ONFH who underwent double-channel CD combined with medullary cavity irrigation and admitted between January 2024 and October 2024 (CD+irrigation group). According to a 1: 2 ratio, 54 patients (60 hips) who underwent simple CD and were matched in terms of age, gender, and body mass index (BMI) were included as the control (CD group). There was no significant difference in baseline data such as age, gender, BMI, affected side, ONFH type, preoperative Association Research Circulation Osseous (ARCO) stage, bone marrow edema stage, visual analogue scale (VAS) score for pain, and Harris score between the two groups ( >0.05). The postoperative discharge time and occurrence of complications were recorded for both groups. The VAS scores before operation and at discharge after operation were compared, and the differences between pre- and post-operation (change values) were calculated for intergroup comparison. The Harris scores before operation and at discharge and 3 months after operation were also compared. During follow-up, X-ray film, CT, and MRI were performed for reexamination. The ARCO stage and bone marrow edema stage were evaluated at 3 months after operation and compared with those before operation to determine whether there was radiological progression or relief.

RESULTS

All incisions in both groups healed by first intention after operation, with no infection, femoral neck fracture, or other operation-related complications. All patients were followed up, and the follow-up time of the CD+irrigation group was (146.8±27.7) days, and that of the CD group was (164.3±48.2) days; there was no significant difference between the two groups ( =1.840, =0.069). There was no significant difference in the length of hospital stay between the two groups ( >0.05). At discharge after operation, the VAS score of the CD+irrigation group was significantly lower than that of the CD group ( <0.05), and the change value was significantly higher than that of the CD group ( <0.05). The Harris scores at discharge and 3 months after operation in the CD+irrigation group were significantly higher than those in the CD group ( <0.05). The Harris score gradually increased with time, and the differences between different time points were significant ( <0.05). Radiological reexamination showed that there was no significant difference in the ARCO stage and the incidence of radiological progression between the two groups at 3 months after operation ( >0.05); however, the bone marrow edema stage and the degree of bone marrow edema relief in the CD+irrigation group were better than those in the CD group, with significant differences ( <0.05).

CONCLUSION

Double-channel CD combined with medullary cavity irrigation can significantly alleviate hip joint pain and improve joint function in patients with non-traumatic ONFH, reduce the degree of bone marrow edema in the femoral head, and delay the progression of ONFH.

摘要

目的

比较双通道髓芯减压(CD)联合髓腔冲洗与单纯CD对非创伤性股骨头坏死(ONFH)塌陷进展及临床结局的影响。

方法

对2024年1月至2024年10月期间收治的19例(30髋)接受双通道CD联合髓腔冲洗的非创伤性ONFH患者的临床资料进行回顾性分析(CD+冲洗组)。按照1∶2的比例,纳入54例(60髋)接受单纯CD且年龄、性别、体重指数(BMI)相匹配的患者作为对照组(CD组)。两组患者的年龄、性别、BMI、患侧、ONFH类型、术前国际骨循环研究学会(ARCO)分期、骨髓水肿分期、疼痛视觉模拟评分(VAS)、Harris评分等基线资料比较,差异均无统计学意义(>0.05)。记录两组患者术后出院时间及并发症发生情况。比较两组患者术前及术后出院时的VAS评分,并计算术前与术后的差值(变化值)进行组间比较。比较两组患者术前、术后出院时及术后3个月的Harris评分。随访期间,行X线片、CT及MRI复查。于术后3个月评估ARCO分期及骨髓水肿分期,并与术前比较,判断有无影像学进展或缓解。

结果

两组患者术后切口均一期愈合,无感染、股骨颈骨折及其他手术相关并发症发生。所有患者均获随访,CD+冲洗组随访时间为(146.8±27.7)天,CD组为(164.3±48.2)天;两组比较,差异无统计学意义(=1.840,=0.069)。两组患者住院时间比较,差异无统计学意义(>0.05)。术后出院时,CD+冲洗组VAS评分显著低于CD组(<0.05),变化值显著高于CD组(<0.05)。CD+冲洗组术后出院时及术后3个月的Harris评分均显著高于CD组(<0.05)。Harris评分随时间逐渐升高,不同时间点比较,差异有统计学意义(<0.05)。影像学复查显示,术后3个月两组患者ARCO分期及影像学进展发生率比较,差异无统计学意义(>0.05);但CD+冲洗组骨髓水肿分期及骨髓水肿缓解程度均优于CD组,差异有统计学意义(<0.05)。

结论

双通道CD联合髓腔冲洗可显著减轻非创伤性ONFH患者髋关节疼痛,改善关节功能,减轻股骨头骨髓水肿程度,延缓ONFH进展。

相似文献

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[Clinical study of double-channel core decompression combined with medullary cavity irrigation for non-traumatic osteonecrosis of femoral head].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2025 Apr 15;39(4):399-405. doi: 10.7507/1002-1892.202501039.
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