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[通过手术髋关节脱位入路植入骨移植与股骨头缺血性坏死ARCO分期的髓芯减压及骨移植对比]

[Impacting bone graft via surgical hip dislocation approach versus core decompression and bone graft for avascular necrosis of femoral head at ARCO stage ].

作者信息

Sun Haizhong, Wei Biaofang

机构信息

Guangzhou University of Chinese Medicine, Guangzhou Guangdong, 510006, P.R.China;Specialized Subject of Femoral Head, the People's Hospital of Linyi, Linyi Shandong, 276000, P.R.China.

Specialized Subject of Femoral Head, the People's Hospital of Linyi, Linyi Shandong, 276000,

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2019 May 15;33(5):531-536. doi: 10.7507/1002-1892.201901047.

Abstract

OBJECTIVE

To compare the effectiveness of sequestrum clearance and impacting bone graft via surgical hip dislocation approach and core decompression and bone graft for avascular necrosis of the femoral head (ANFH) at Association Research Circulation Osseous (ARCO) stage Ⅲ.

METHODS

A clinical data of 60 patients (69 hips) of non-traumatic ANFH at ARCO stage Ⅲ, which met the inclusion criteria between October 2013 and April 2016, was retrospectively analyzed. Among them, 24 patients (28 hips) were treated with sequestrum clearance and impacting bone graft via surgical hip dislocation approach (group A); and 36 patients (41 hips) were treated with core decompression, sequestrum clearance, impacting bone graft, and nonvascular fibular allograft supporting (group B). There was no significant difference in gender, age, disease duration, affected side, type and stage of the ANFH, and preoperative Harris hip score and visual analogue scale (VAS) score between the two groups ( >0.05). After operation, the function of the hip was evaluated by Harris hip score, imaging examination was performed to observe the femoral head shape and evaluate whether the hip preserving success.

RESULTS

The incisions of two groups healed by first intention. All patients were followed up. The follow-up time was 12-48 month (mean, 25.8 months) in group A and 12-54 months (mean, 26.4 months) in group B. At last follow-up, 5 hips in group A were classified as clinical failure, femoral head survival rate was 82.1%, the median survival time was 43 months. While 19 hips in group B were classified as clinical failure, femoral head survival rate was 53.7%, the median survival time was 42 months. There was significant difference in survival curve distribution between the two groups ( = 4.123, =0.042), and the surgical procedures of group A was superior to group B. In the two groups, the Harris hip scores at last follow-up were significantly higher than preoperative ones ( <0.05), and VAS scores were significantly lower than preoperative ones ( <0.05). There was no significant difference in Harris hip score and VAS score at last follow-up between the two groups ( >0.05). All grafted bones got fusion according to the X-ray films, and there was no significant difference in the fusion time between the two groups ( =0.752, =0.456). In group A, greater trochanter bone cutting were healed well; and the heterotopic ossification around the hip joint occurred in 1 case.

CONCLUSION

The surgery of impacting bone graft via surgical hip dislocation approach and core decompression and bone graft can be applied to treat ANFH at ARCO stage ⅢA which was mild collapse and satisfactory effectiveness can be obtained. While for the patients of ANFH at ARCO stage Ⅲ B with severe collapse, the hip survival rate of the former is better than that of the latter.

摘要

目的

比较手术髋关节脱位入路清除死骨及打压植骨与髓芯减压及植骨治疗协会研究循环骨(ARCO)Ⅲ期股骨头缺血性坏死(ANFH)的疗效。

方法

回顾性分析2013年10月至2016年4月间符合纳入标准的60例(69髋)ARCOⅢ期非创伤性ANFH患者的临床资料。其中,24例(28髋)采用手术髋关节脱位入路清除死骨及打压植骨治疗(A组);36例(41髋)采用髓芯减压、清除死骨、打压植骨及非血管化腓骨移植支撑治疗(B组)。两组患者在性别、年龄、病程、患侧、ANFH的类型和分期以及术前Harris髋关节评分和视觉模拟量表(VAS)评分方面差异均无统计学意义(P>0.05)。术后采用Harris髋关节评分评估髋关节功能,行影像学检查观察股骨头形态并评估保髋是否成功。

结果

两组切口均一期愈合。所有患者均获随访。A组随访时间为12~48个月(平均25.8个月),B组随访时间为12~54个月(平均26.4个月)。末次随访时,A组有5髋被判定为临床失败,股骨头生存率为82.1%,中位生存时间为43个月。B组有19髋被判定为临床失败,股骨头生存率为53.7%,中位生存时间为42个月。两组生存曲线分布差异有统计学意义(χ²=4.123,P=0.042),A组手术方式优于B组。两组末次随访时Harris髋关节评分均显著高于术前(P<0.05),VAS评分均显著低于术前(P<0.05)。两组末次随访时Harris髋关节评分和VAS评分差异无统计学意义(P>0.05)。所有移植骨根据X线片均获融合,两组融合时间差异无统计学意义(t=0.752,P=0.456)。A组大转子截骨愈合良好;髋关节周围异位骨化1例。

结论

手术髋关节脱位入路打压植骨及髓芯减压植骨术可应用于治疗ARCOⅢA期轻度塌陷的ANFH,可获得满意疗效。而对于ARCOⅢB期塌陷严重的ANFH患者,前者的保髋生存率优于后者。

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