Stefanits K, Kuhn E, Csere T
Strahlentherapie. 1985 Jul;161(7):406-9.
The authors present the results of investigations of the immune reactivity of 72 patients irradiated for testicle tumors. The responses to tuberculin and DNCB (2.4-dinitrochlorobenzol) were examined before the treatment, within twelve months after radiotherapy and three years after radiotherapy and when metastases appeared. After radiotherapy, the number of positive responses was slightly decreased in both examination methods, but the difference was in no case significant. Patients with metastases showed a significantly decreased response to DNCB compared to the results obtained before radiotherapy. 5.6% of the patients had suffered from herpes zoster. The incidence of other infective diseases was not increased. The conclusion is drawn that the moderate immunosuppression caused by radiotherapy does not exert any influence on the further way of living of patients with testicle tumors.
作者展示了72例接受睾丸肿瘤放疗患者的免疫反应性调查结果。在治疗前、放疗后十二个月内、放疗后三年以及出现转移时,检测了对结核菌素和二硝基氯苯(DNCB)的反应。放疗后,两种检测方法中阳性反应的数量均略有下降,但差异均无统计学意义。与放疗前的结果相比,出现转移的患者对DNCB的反应明显降低。5.6%的患者曾患带状疱疹。其他感染性疾病的发病率未增加。得出的结论是,放疗引起的中度免疫抑制对睾丸肿瘤患者的后续生活方式没有任何影响。