Gaitero Maria Victória Candida, de Mira Ticiana Aparecida Alves, Gondim Edna Jéssica Lima, do Nascimento Simony Lira, Surita Fernanda Garanhani
Universidade Estadual de Campinas CampinasSP Brazil Universidade Estadual de Campinas, Campinas, SP, Brazil.
Universidade Federal do Ceará FortalezaCE Brazil Universidade Federal do Ceará, Fortaleza, CE, Brazil.
Rev Bras Ginecol Obstet. 2025 Mar 17;47. doi: 10.61622/rbgo/2025rbgo3. eCollection 2025.
This study aimed to investigate the effect of low-level laser therapy (LLLT) on nipple trauma and pain during breastfeeding through a systematic review with a meta-analysis of selected studies.
A thorough search was conducted on March 22, 2022, using the databases PubMed, SciELO, LILACS, PEDro, CINAHL, EMBASE, ScienceDirect, Scopus, Google Scholar, MEDLINE, the Cochrane Library, Clinical Trials, Web of Science, TRIP, DARE, and ProQuest. The search terms included various combinations of low-level laser therapy, nipple pain, nipple trauma, and breastfeeding.
Out of 107 articles identified, only three controlled and randomized clinical trials was included. The extracted data encompassed breast and trauma characteristics, treatment types, outcomes (pain and healing process), evaluation tools, LLLT usage, laser brand, and parameters.
Data extraction was performed using RAYYAN for systematic reviews. The risk of bias in the studies was evaluated.
Pain was measured using the visual analog scale (VAS). The included studies did not use validated tools for assessing physical conditions. All studies employed LLLT with a 660-nm wavelength, though there were variations in equipment power, energy dose, and application methods. The meta-analysis revealed an average difference of -0.60 points (95% CI: -1.52 to 0.31) in the VAS pain scores between the LLLT and control groups. No heterogeneity was observed among the studies (I2=0%), indicating no significant difference in pain relief between LLLT (red light) and control groups.
LLLT may offer a promising option for managing breastfeeding-related complications, though further research is required.
本研究旨在通过对所选研究进行系统评价和荟萃分析，探讨低强度激光疗法（LLLT）对母乳喂养期间乳头创伤和疼痛的影响。
2022年3月22日，使用PubMed、SciELO、LILACS、PEDro、CINAHL、EMBASE、ScienceDirect、Scopus、谷歌学术、MEDLINE、Cochrane图书馆、临床试验、科学网、TRIP、DARE和ProQuest等数据库进行了全面检索。检索词包括低强度激光疗法、乳头疼痛、乳头创伤和母乳喂养的各种组合。
在识别出的107篇文章中，仅纳入了三项对照随机临床试验。提取的数据包括乳房和创伤特征、治疗类型、结果（疼痛和愈合过程）、评估工具、LLLT使用情况、激光品牌和参数。
使用RAYYAN进行系统评价的数据提取。评估了研究中的偏倚风险。
使用视觉模拟量表（VAS）测量疼痛。纳入的研究未使用经过验证的工具来评估身体状况。所有研究均采用波长为660nm的LLLT，尽管设备功率、能量剂量和应用方法存在差异。荟萃分析显示，LLLT组和对照组之间的VAS疼痛评分平均差异为-0.60分（95%CI：-1.52至0.31）。研究之间未观察到异质性（I2=0%），表明LLLT（红灯）组和对照组在疼痛缓解方面无显著差异。
LLLT可能为管理与母乳喂养相关的并发症提供一个有前景的选择，尽管还需要进一步研究。
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