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用于治疗细菌感染的产气光催化剂

Gas-Generating Photocatalytic Agents for Bacterial Infection Treatment.

作者信息

Hu Yanling, Yang Kaiqi, Li Ning, Yang Dongliang, Dong Heng

机构信息

College of Life and Health, Nanjing Polytechnic Institute, Nanjing 210048, China.

College of Material Engineering, Fujian Agriculture and Forestry University, Fuzhou 350108, China.

出版信息

Research (Wash D C). 2025 Apr 16;8:0672. doi: 10.34133/research.0672. eCollection 2025.

Abstract

Bacterial infections markedly strain healthcare systems financially, compounded by the rise of drug-resistant strains and biofilm-associated infections. Gas therapy has emerged as a notable solution, disrupting biofilms and targeting resistant bacteria through controlled gas release mechanisms. However, achieving precise and controlled gas release remains a critical challenge for the successful implementation of gas therapy. In this perspective, we summarize recent advancements in photocatalytic gas release for treating bacterial infections. It also outlines crucial challenges that must be addressed to fully leverage this promising therapeutic strategy, enhancing its precision and effectiveness in clinical settings.

摘要

细菌感染给医疗系统带来了巨大的经济负担,耐药菌株的增加和生物膜相关感染更是雪上加霜。气体疗法已成为一种显著的解决方案,它通过可控的气体释放机制破坏生物膜并靶向耐药细菌。然而,实现精确和可控的气体释放仍然是气体疗法成功实施的关键挑战。从这个角度出发,我们总结了用于治疗细菌感染的光催化气体释放的最新进展。它还概述了要充分利用这一有前景的治疗策略必须解决的关键挑战,以提高其在临床环境中的精确性和有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/407e/12000652/6f5d95e94bd0/research.0672.fig.001.jpg

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