Pilinskaia M A
Tsitol Genet. 1985 May-Jun;19(3):183-7.
The present study shows that the culture of human peripheral lymphocytes may be used as target cells for detecting the whole urine mutagenic activity. It is established that urine from healthy control cigarette smokers and from non-smoking greenhouse workers contacting with a complex of different pesticides significantly increased frequency of chromosome aberrations in the approbated test-system. The data obtained give evidence for the presence of genetically active substances in organisms of the examined individuals.
本研究表明，人外周血淋巴细胞培养物可作为检测全尿致突变活性的靶细胞。已确定，在经过验证的测试系统中，来自健康对照吸烟者以及接触多种不同农药的非吸烟温室工人的尿液，显著增加了染色体畸变频率。所获得的数据证明，被检测个体的机体中存在具有遗传活性的物质。
