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一项探索性随机试验,评估纳地收束式呼吸法作为辅助手段与标准非药物管理对高血压患者的效果比较

An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.

作者信息

Mittal Gauri, Pathania Monika, Bhardwaj Praag, Dhar Minakshi, Khapre Meenakshi, Mittal Sunita

机构信息

Department of Pharmacology, All India Institute of Medical Science Rishikesh, Uttarakhand, India.

Department of Geriatric Medicine, All India Institute of Medical Science Rishikesh, Uttarakhand, India.

出版信息

Ann Neurosci. 2025 Apr 14:09727531251318810. doi: 10.1177/09727531251318810.

Abstract

BACKGROUND

Nadi shodhan pranayama, which is also known as Anulom-vilom pranayama or alternate nostril breathing, has been demonstrated to elicit a decrease in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate, owing to its stress-reducing effects. One of the most promising quantitative markers of autonomic activity is heart rate variability (HRV).

PURPOSE

This study was done to study the immediate and long-term effects of 10 minutes of nadi shodhan pranayama, preceded by two minutes of yogic deep abdominal breathing, on blood pressure and other autonomic parameters.

METHODS

Baseline parameters of BP, HRV, Pittsburgh Sleep Quality Index (PSQI) and Hamilton Anxiety Rating Scale (HAM-A) were measured at first visit. Patients were randomised into test and control groups, and the test group was given intervention. BP and HRV were measured once again immediately after intervention for test subjects. After six weeks, BP, HRV, PSQI and HAM-A were repeated.

RESULTS

Immediately after the intervention, the test group showed a significant reduction in SBP, DBP and mean heart rate (MHR) with an increase in R-R interval, standard deviation of the NN interval (SDNN), the square root of the mean squared differences of successive NN intervals and high frequency. At follow-up, the test group had a lower SBP and low frequency/high frequency ratio and a higher SDNN and total power, compared to the control group.

CONCLUSION

The practice of nadi shodhan pranayama, preceded by two minutes of yogic deep abdominal breathing, reduced the systolic and diastolic BP and improved HRV-related autonomic parameters, in patients of hypertension on pharmacological therapy, immediately after 10 minutes of practice and after 10 minutes of daily practice for six weeks.

摘要

背景

纳地净化呼吸法,也被称为顺腹式呼吸法或交替鼻孔呼吸法,因其减压效果已被证明可使收缩压(SBP)、舒张压(DBP)和心率降低。自主神经活动最有前景的定量标志物之一是心率变异性(HRV)。

目的

本研究旨在探讨在进行两分钟瑜伽深度腹式呼吸后进行10分钟纳地净化呼吸法对血压和其他自主神经参数的即时和长期影响。

方法

首次就诊时测量血压、HRV、匹兹堡睡眠质量指数(PSQI)和汉密尔顿焦虑量表(HAM-A)的基线参数。将患者随机分为试验组和对照组,试验组接受干预。试验对象干预后立即再次测量血压和HRV。六周后,重复测量血压、HRV、PSQI和HAM-A。

结果

干预后立即发现,试验组的SBP、DBP和平均心率(MHR)显著降低,R-R间期、NN间期标准差(SDNN)、连续NN间期均方根差和高频增加。随访时,与对照组相比,试验组的SBP和低频/高频比值较低,SDNN和总功率较高。

结论

对于接受药物治疗的高血压患者,在进行两分钟瑜伽深度腹式呼吸后进行纳地净化呼吸法练习,在练习10分钟后以及每天练习10分钟持续六周后,可降低收缩压和舒张压,并改善与HRV相关的自主神经参数。

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