全氟碳化合物（FDA 20）与肢体隔离灌注体外循环。

Perfluorocarbone (FDA 20) and extracorporeal circuit of isolated extremity perfusion.

作者信息

Hild P, de Toma G, Schwemmle K, Pfannkuch F, Beisbarth H

出版信息

Tumori. 1985 Jun 30;71(3):267-70. doi: 10.1177/030089168507100308.

Abstract

The applicability of Fluosol DA 20 as a perfusion fluid was investigated in the isolated limb perfusion of 14 mongrel dogs and its performance compared with that of diluted blood. Control of perfusion parameters permitted a direct comparison of the two perfusion liquids. Muscle tissue, blood and perfusate were analyzed for pH, pO2, pCO2, O2 content, lactate, pyruvate, ATP and creatine phosphate. Due to given experimental conditions, the pH values of the perfusion liquid and muscle tissue were in a slightly acidic range. The oxygen uptake of the perfusion liquids and the oxygenation of tissue was satisfactory, the metabolism of the muscle tissue was not disrupted.

摘要

在14只杂种狗的离体肢体灌注中研究了氟碳化合物DA 20作为灌注液的适用性，并将其性能与稀释血液的性能进行了比较。通过控制灌注参数，可以直接比较两种灌注液。对肌肉组织、血液和灌注液进行了pH、pO2、pCO2、O2含量、乳酸、丙酮酸、ATP和磷酸肌酸的分析。由于给定的实验条件，灌注液和肌肉组织的pH值处于略呈酸性的范围内。灌注液的氧摄取和组织的氧合情况良好，肌肉组织的代谢未受到干扰。